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Dimestrol

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Dimestrol
Clinical data
Trade namesDepot-Ostromon; Synthila
Other namesDianisylhexene; 4,4'-Dimethoxy-α,α'-diethylstilbene; Diethylstilbestrol dimethyl ether; Dimethoxydiethylstilbestrol; (E)-4,4'-(1,2-Diethylethylene)dianisole
Drug classNonsteroidal estrogen; Estrogen ether
Identifiers
  • 1-methoxy-4-[(E)-4-(4-methoxyphenyl)hex-3-en-3-yl]benzene
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.004.542 Edit this at Wikidata
Chemical and physical data
FormulaC20H24O2
Molar mass296.403 g/mol g·mol−1
3D model (JSmol)
  • CCC(=C(CC)C1=CC=C(C=C1)OC)C2=CC=C(C=C2)OC
  • InChI=1S/C20H24O2/c1-5-19(15-7-11-17(21-3)12-8-15)20(6-2)16-9-13-18(22-4)14-10-16/h7-14H,5-6H2,1-4H3/b20-19+
  • Key:VQOAQMIKPYNCMV-FMQUCBEESA-N

Dimestrol (brand names Depot-Ostromon, Synthila), also known as dianisylhexene, 4,4'-dimethoxy-α,α'-diethylstilbene, diethylstilbestrol dimethyl ether, and dimethoxydiethylstilbestrol, is a synthetic nonsteroidal estrogen of the stilbestrol group which is related to diethylstilbestrol.[1][2] It has been used to induce the development of female secondary sexual characteristics in the case of female delayed puberty or hypogonadism.[3] The drug has also been used as a fattening agent in livestock.[4]

See also

References

  1. ^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 396. ISBN 978-1-4757-2085-3.
  2. ^ William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 1324–. ISBN 978-0-8155-1856-3.
  3. ^ Soviet Genetics. Consultants Bureau. 1982.
  4. ^ National Research Council (U.S.). Committee on Animal Nutrition (1953). Hormonal Relationships and Applications in the Production of Meats, Milk, and Eggs: A Report of the Committee on Animal Nutrition. National Academies. pp. 5–13. NAP:14582.