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|Chemical and physical data|
|Molar mass||436.56 g/mol|
|3D model (Jmol)|
|(what is this?)|
Estropipate (INN, USAN, BAN) (brand names Harmogen, Improvera, Ogen, Ortho-Est, many others), also known as piperazine estrone sulfate, is a semi-synthetic, steroidal estrogen that is used mainly in hormone replacement therapy in the treatment of symptoms of menopause. It is a salt of estrone sulfate and piperazine, and is hydrolyzed into estrone in the body.
Estropipate is used to:
- Alleviate symptoms of menopause as hormone replacement therapy
- Treat some types of infertility
- Treat some conditions leading to underdevelopment of female sexual characteristics
- Treat vaginal atrophy
- Treat some types of breast cancer (particularly in men and postmenopausal women)
- Treat prostate cancer
- Prevent osteoporosis
- J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 900–. ISBN 978-1-4757-2085-3.
- I.K. Morton; Judith M. Hall (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 114–. ISBN 978-94-011-4439-1.