Estradiol propoxyphenylpropionate

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Estradiol propoxyphenylpropionate
Clinical data
Trade namesDurovex
Other namesEPPP; Estradiol 17-(4-propoxyphenyl)propanoate; Estradiol p-propoxyhydrocinnamate
Routes of
administration
Intramuscular injection
Drug classEstrogen; Estrogen ester
Identifiers
  • [(8R,9S,13S,14S,17S)-3-Hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 3-(4-propoxyphenyl)propanoate
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC30H38O4
Molar mass462.630 g·mol−1
3D model (JSmol)
  • CCCOc1ccc(CCC(=O)O[C@H]2CC[C@H]3[C@@H]4CCc5cc(O)ccc5[C@H]4CC[C@]23C)cc1
  • InChI=1S/C30H38O4/c1-3-18-33-23-9-4-20(5-10-23)6-15-29(32)34-28-14-13-27-26-11-7-21-19-22(31)8-12-24(21)25(26)16-17-30(27,28)2/h4-5,8-10,12,19,25-28,31H,3,6-7,11,13-18H2,1-2H3/t25-,26-,27+,28+,30+/m1/s1
  • Key:JNWIUSBBFNMZRQ-BOJCFLQHSA-N

Estradiol propoxyphenylpropionate (EPPP), sold under the brand name Durovex, is an estrogen medication and estrogen ester which is no longer marketed.[1] It is the C17β propoxyphenylpropionate (propoxyhydrocinnamate) ester of estradiol.[1] It is a long-acting depot estrogen.[2][3]

See also

References

  1. ^ a b J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 898. ISBN 978-1-4757-2085-3.
  2. ^ Baker, A. P.; Bergman, F.; Josefsson, B.; Paul, K. G. (1967). "Studies on eosinophil granulocytes. 3. Steroid hormones and number of eosinophils in the uterus of the mouse and rat". Acta Endocrinologica. 56 (2): 221–224. doi:10.1530/acta.0.0560221. ISSN 0804-4643. PMID 6071489.
  3. ^ Å. Åkeson; A. Ehrenberg (17 May 2014). Structure and Function of Oxidation–Reduction Enzymes: Proceedings of the Wenner-Gren Symposium Held at the Wenner-Gren Center, Stockholm, 23–27 August, 1970. Elsevier. pp. 216–. ISBN 978-1-4831-4755-0.