Estradiol salicylate

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Estradiol salicylate
Estradiol salicylate.svg
Clinical data
SynonymsEstradiol 3-salicylate
Routes of
By mouth[1]
Drug classEstrogen; Estrogen ester
CAS Number
PubChem CID
Chemical and physical data
Molar mass392.495 g/mol g·mol−1
3D model (JSmol)

Estradiol salicylate, or estradiol 3-salicylate, is a synthetic estrogen and estrogen ester – specifically, the C3 salicylic acid ester of estradiol – which was described in the late 1980s and was never marketed.[1] It is a metabolite of estradiol acetylsalicylate, which appears to be very rapidly hydrolyzed into estradiol salicylate.[1]

See also[edit]


  1. ^ a b c Hussain MA, Aungst BJ, Shefter E (January 1988). "Prodrugs for improved oral beta-estradiol bioavailability". Pharm. Res. 5 (1): 44–7. doi:10.1023/A:1015863412137. PMID 3244608.