IL2RA
Template:PBB Interleukin-2 receptor alpha chain is a protein that in humans is encoded by the IL2RA gene.[1]
Infection by the protozoan Trypanosoma cruzi causes Chagas disease, characterized by a reduction in the amount of IL2RA expressed on the surface of immune cells. This leads to chronic immune suppression, becoming increasingly severe over the course of many years and ultimately resulting in death if left untreated.
References
- ^ Leonard WJ, Donlon TA, Lebo RV, Greene WC (1985). "Localization of the gene encoding the human interleukin-2 receptor on chromosome 10". Science. 228 (4707): 1547–9. doi:10.1126/science.3925551. PMID 3925551.
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Further reading
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