CCRL1

From Wikipedia, the free encyclopedia
Jump to: navigation, search
ACKR4
Identifiers
Aliases ACKR4, CC-CKR-11, CCBP2, CCR-11, CCR10, CCR11, CCRL1, CCX CKR, CCX-CKR, CKR-11, PPR1, VSHK1, atypical chemokine receptor 4
External IDs MGI: 2181676 HomoloGene: 49474 GeneCards: 51554
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_178445
NM_016557

NM_145700

RefSeq (protein)

NP_057641.1
NP_848540.1

NP_663746.2

Location (UCSC) Chr 3: 132.6 – 132.62 Mb Chr 9: 104.08 – 104.13 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

C-C chemokine receptor type 11 is a protein that in humans is encoded by the CCRL1 gene.[1][2]

The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. Alternatively spliced transcript variants encoding the same protein have been described.[2]

References[edit]

  1. ^ Khoja H, Wang G, Ng CT, Tucker J, Brown T, Shyamala V (May 2000). "Cloning of CCRL1, an orphan seven transmembrane receptor related to chemokine receptors, expressed abundantly in the heart". Gene 246 (1–2): 229–38. doi:10.1016/S0378-1119(00)00076-7. PMID 10767544. 
  2. ^ a b "Entrez Gene: CCRL1 chemokine (C-C motif) receptor-like 1". 

Further reading[edit]


This article incorporates text from the United States National Library of Medicine, which is in the public domain.