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Bendiocarb

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Bendiocarb
Names
IUPAC name
(2,2-Dimethyl-1,3-benzodioxol-4-yl) N-methylcarbamate
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.041.091 Edit this at Wikidata
KEGG
UNII
  • InChI=1/C11H13NO4/c1-11(2)15-8-6-4-5-7(9(8)16-11)14-10(13)12-3/h4-6H,1-3H3,(H,12,13)
    Key: XEGGRYVFLWGFHI-UHFFFAOYAG
  • O=C(Oc1cccc2OC(Oc12)(C)C)NC
Properties
C11H13NO4
Molar mass 223.23 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Bendiocarb is an acutely toxic carbamate insecticide used in public health and agriculture and is effective against a wide range of nuisance and disease vector insects. Many bendiocarb products are or were sold under the tradenames "Ficam" and "Turcam."

All bendiocarb-containing products in the United States were recently cancelled, after its manufacturers voluntarily chose to pull their products off the market, rather than conduct additional safety studies required by the EPA.[1] In other countries, it is still used in homes, industrial plants, and food storage sites to control bedbugs, mosquitoes, flies, wasps, ants, fleas, cockroaches, silverfish, and ticks but can be used against a wide variety of insects as well as snails and slugs. It is one of 12 insecticides recommended by the World Health Organization for use in malaria control.[2]

Bendiocarb is not considered to be carcinogenic, but it is acutely toxic. Like other carbamates, it reversibly inhibits acetylcholinesterase, an enzyme required for normal transmission of nerve impulses. Bendiocarb binds to the active site of this enzyme leading to an accumulation of acetylcholine, which is required for the transmission of nerve impulses, at nerve muscle sites.[1]

Bendiocarb was invented in 1971 and was first introduced into the market by Fisons Ltd. It is currently marketed by Bayer CropScience and Kuo Ching under various trade names: Ficam, Dycarb, Garvox, Turcam, Niomil, Seedox, Tattoo

Bendiocarb is highly toxic to birds and fish. In mammalian tissue, carbamates are generally excreted rapidly and do not accumulate.[1]

References

  1. ^ a b c R.E.D. Facts: Bendiocarb U.S. EPA, September 1999.
  2. ^ Sadasivaiah, Shobha; Tozan, Yesim; Breman, Joel G. (December 1, 2007), "Dichlorodiphenyltrichloroethane (DDT) for Indoor Residual Spraying in Africa: How Can It Be Used for Malaria Control?", Am. J. Trop. Med. Hyg., 77 (Suppl 6): 249–263

External links

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