Quinestradol

Quinestradol
Clinical data
Trade names	Colpovis, Colpovister, Pentovis
Other names	Quinestradiol; Quinestriol; Estriol 3-cyclopentyl ether; E3CPE
Routes of; administration	By mouth
Drug class	Estrogen; Estrogen ether
ATC code	None;
Identifiers
	IUPAC name (8R,9S,13S,14S,16R,17R)-3-cyclopentyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol;
CAS Number	1169-79-5 ;
PubChem CID	14431;
ChemSpider	16735993;
UNII	422L8173W8;
CompTox Dashboard (EPA)	DTXSID30878638 ;
ECHA InfoCard	100.013.294
Chemical and physical data
Formula	C23H32O3
Molar mass	356.506 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC12CCC3C(C1CC(C2O)O)CCC4=C3C=CC(=C4)OC5CCCC5;
	InChI InChI=1S/C23H32O3/c1-23-11-10-18-17-9-7-16(26-15-4-2-3-5-15)12-14(17)6-8-19(18)20(23)13-21(24)22(23)25/h7,9,12,15,18-22,24-25H,2-6,8,10-11,13H2,1H3/t18-,19-,20+,21-,22+,23+/m1/s1; Key:ODYKCPYPRCJXLY-PZORDLPLSA-N;

Quinestradol (INNTooltip International Nonproprietary Name, BANTooltip British Approved Name) (brand names Colpovis, Colpovister, Pentovis), also known as quinestradiol or quinestriol, as well as estriol 3-cyclopentyl ether (E3CPE), is a synthetic estrogen and estrogen ether which is no longer marketed.^[1]^[2]^[3]^[4] It is the 3-cyclopentyl ether of estriol.^[1] The medication has been studied in the treatment of stress incontinence in elderly women, with effectiveness observed.^[3]^[4]

References

^ ^a ^b Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 899–. ISBN 978-1-4757-2085-3.
^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 905–. ISBN 978-3-88763-075-1.
^ ^a ^b Crosignani PG, Paoletti R, Sarrel PM, Wenger NK (6 December 2012). Women's Health in Menopause: Behaviour, Cancer, Cardiovascular Disease, Hormone Replacement Therapy. Springer Science & Business Media. pp. 245–. ISBN 978-94-011-1024-2.
^ ^a ^b Seifer DB (27 July 1999). Menopause: Endocrinology and Management. Springer Science & Business Media. pp. 161–. ISBN 978-1-59259-246-3.

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[Elks2014-1] Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 899–. ISBN 978-1-4757-2085-3.

[IndexNominum2000-2] Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 905–. ISBN 978-3-88763-075-1.

[CrosignaniPaoletti2012-3] Crosignani PG, Paoletti R, Sarrel PM, Wenger NK (6 December 2012). Women's Health in Menopause: Behaviour, Cancer, Cardiovascular Disease, Hormone Replacement Therapy. Springer Science & Business Media. pp. 245–. ISBN 978-94-011-1024-2.

[Seifer1999-4] Seifer DB (27 July 1999). Menopause: Endocrinology and Management. Springer Science & Business Media. pp. 161–. ISBN 978-1-59259-246-3.

[1]

[2]

[3]

[4]

See also

References