5-MeO-2-TMT

From Wikipedia, the free encyclopedia
Jump to: navigation, search
5-MeO-2-TMT
5-MeO-2,N,N-TMT.svg
Systematic (IUPAC) name
2-(5-methoxy-2-methyl-H-indol-3-yl)-N,N-dimethylethanamine
Clinical data
Legal status ?
Identifiers
CAS number 67292-68-6
ATC code ?
PubChem CID 49756
ChemSpider 45143 YesY
ChEMBL CHEMBL7143 YesY
Chemical data
Formula C14H20N2O 
Mol. mass 232.321 g/mol
 YesY (what is this?)  (verify)

5-Methoxy-2,N,N-trimethyltryptamine (5-MeO-2,N,N-TMT, 5-MeO-TMT) is a psychoactive drug of the tryptamine chemical class which acts as a psychedelic. It was first synthesized by Alexander Shulgin and reported in his book TiHKAL ("Tryptamines i Have Known And Loved").[1] 5-MeO-TMT is claimed to show psychoactive effects at a dosage of 75-150 mg orally, but these are relatively mild compared to those of other similar compounds. This suggests that while the methyl group on the 2-position of the molecule has impaired the binding of metabolic enzymes like monoamine oxidase (MAO), it is also interfering with binding to and/or activation of the serotonin 5-HT2A receptor, the target responsible for mediating the hallucinogenic effects of such compounds.

See also[edit]

References[edit]

External links[edit]