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This page should be headed under "Systanon 250" as it originally was before Medgirl131 messed this page up. (can someone help fix that) - I have rejigged information backed to coherent form and added in ref links.
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| caption =
| caption =


⚫
| drug_name = Sustanon 250
<!--Combo data-->
| type = combo
⚫
| drug_name = TP/TPP/TiC/TD
| component1 = Testosterone propionate
| class1 = [[Androgen]]; [[Anabolic steroid]]
⚫
| component2 = Testosterone phenylpropionate
| class2 = [[Androgen]]; [[Anabolic steroid]]
| component3 = Testosterone isocaproate
| class3 = [[Androgen]]; [[Anabolic steroid]]
| component4 = Testosterone decanoate
| class4 = [[Androgen]]; [[Anabolic steroid]]


<!-- Clinical data -->
<!-- Clinical data -->
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}}
}}


'''Sustanon''' is a trade name owned by Organon Pharmaceuticals for oil-based injectable blends of [[ester]]ified [[testosterone (medication)|testosterone]] compounds.
'''Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone decanoate''' ('''TP/TPP/TiC/TD'''), sold under the brand name '''Sustanon 250''' ([[Organon International|Organon]]) among others, is an [[injection (medicine)|injectable]] [[combination drug|combination]] [[medication]] of four [[testosterone ester]]s, all of which are [[androgen]]s/[[anabolic steroid]]s. They include:



'''Sustanon 250''' is a blend of four [[ester]]ified [[testosterone (medication)|testosterone]] compounds: <ref>{{cite web | url=https://www.medicines.org.uk/emc/product/5373/smpc | title= Sustanon 250, solution for injection | access-date=2019-06-15}}</ref>
* 30&nbsp;mg [[testosterone propionate]]
* 30&nbsp;mg [[testosterone propionate]]
* 60&nbsp;mg [[testosterone phenylpropionate]]
* 60&nbsp;mg [[testosterone phenylpropionate]]
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* 100&nbsp;mg [[testosterone decanoate]]
* 100&nbsp;mg [[testosterone decanoate]]


They are provided as an [[oil solution]] and are administered by [[intramuscular injection]]. The different testosterone esters provide for different [[elimination half-life|elimination half-lives]] in the body. [[Esterification]] of [[testosterone (medication)|testosterone]] provides for a sustained but non-linear release of testosterone hormone from the injection depot into the [[blood plasma|circulation]].


'''Sustanon 100''' was similar, though with three esters. This smaller dose was usually for [[Pediatrics|pediatric]] use.
Sustanon is the preferred method of testosterone replacement in the [[United Kingdom]] as detailed in the [[British National Formulary]].{{Citation needed|date=November 2010}} There was a brief shortage of Sustanon 250 during late 2011, due to licensing problems,<ref>http://www.oxfordshirepct.nhs.uk/professional-resources/prescribing/prescribing-points/documents/PrescribingPointsJuly11Vol206.pdf {{dead link|date=April 2014}}</ref> and a further shortage in mid-2012 due to manufacturing problems.{{medcn|date=August 2016}}
* 20&nbsp;mg testosterone propionate
⚫
* 40&nbsp;mg testosterone phenylpropionate
* 40&nbsp;mg testosterone isocaproate

Sustanon 100 has not been produced since 2009.<ref>{{cite web|title=Discontinuation of Sustanon 100 (testosterone replacement therapy) |url=http://www.nelm.nhs.uk/en/NeLM-Area/News/2009---March/09/Discontinuation-of-Sustanon-100-testosterone-replacement-therapy/ |publisher=NeLM |accessdate=9 August 2016 |deadurl=yes |archiveurl=https://web.archive.org/web/20090929003710/http://www.nelm.nhs.uk/en/NeLM-Area/News/2009---March/09/Discontinuation-of-Sustanon-100-testosterone-replacement-therapy/ |archivedate=29 September 2009 |df= }}</ref>


The different testosterone esters provide for different half-lives. Esterization of the testosterone molecules provides for a sustained (but non-linear) release of testosterone hormone from the injection depot into the [[blood plasma]]. <ref>{{cite web | url=https://www.steroidsandsarms.com/list-of-injectable-steroids | title= Steroids and SARMS Handbook | access-date=2019-06-15}}</ref>


While the intention of the mixed testosterone esters in Sustanon is to provide more stable serum testosterone levels. <ref>{{Cite news|url=http://answers.steroidline.com/sustanon-info/|title=Pharmacological information. Sust 250 concept|last=|first=|date=2018-06-19|work=|access-date=2018-07-10|language=en-US}}</ref>, a single long-ester testosterone, such as testosterone cypionate or testosterone enanthate, may actually provide more stable serum testosterone levels.{{medcn|date=March 2015}}

Sustanon 250 is one of the most commonly used testosterone replacement treatments prescribed in the UK,US,Canada and Australia.


This form of testosterone is a popular choice of [[anabolic steroid]] among [[bodybuilder]]s and [[sportsperson|athletes]].{{medcn|date=August 2016}}
This form of testosterone is a popular choice of [[anabolic steroid]] among [[bodybuilder]]s and [[sportsperson|athletes]].<ref>{{cite web | url=https://www.steroidsandsarms.com/list-of-injectable-steroids | title= Steroids and SARMS Handbook | access-date=2019-06-15}}</ref>


{{Parenteral durations of androgens/anabolic steroids}}


==See also==
==See also==
* [[Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate]]
* [[Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone caproate]]
* [[List of combined sex-hormonal preparations#Androgens|List of combined sex-hormonal preparations § Androgens]]
* [[List of combined sex-hormonal preparations#Androgens|List of combined sex-hormonal preparations § Androgens]]
* [[Deposterona]]
* [[Omnadren]]
* [[Testoviron Depot]]


==References==
==References==

Revision as of 11:13, 15 June 2019

Sustanon 250
Clinical data
Trade namesDurandrone Forte, Durateston, Prarbolan, Sustanon 250, Sustanon Prolongatum
Other namesTP/TPP/TiC/TD
Routes of
administration		Intramuscular injection
Identifiers
CAS Number
PubChem CID
ChemSpider

Sustanon is a trade name owned by Organon Pharmaceuticals for oil-based injectable blends of esterified testosterone compounds.


Sustanon 250 is a blend of four esterified testosterone compounds: [1]


Sustanon 100 was similar, though with three esters. This smaller dose was usually for pediatric use.

  • 20 mg testosterone propionate
  • 40 mg testosterone phenylpropionate
  • 40 mg testosterone isocaproate

Sustanon 100 has not been produced since 2009.[2]


The different testosterone esters provide for different half-lives. Esterization of the testosterone molecules provides for a sustained (but non-linear) release of testosterone hormone from the injection depot into the blood plasma. [3]


While the intention of the mixed testosterone esters in Sustanon is to provide more stable serum testosterone levels. [4], a single long-ester testosterone, such as testosterone cypionate or testosterone enanthate, may actually provide more stable serum testosterone levels.[medical citation needed]

Sustanon 250 is one of the most commonly used testosterone replacement treatments prescribed in the UK,US,Canada and Australia.

This form of testosterone is a popular choice of anabolic steroid among bodybuilders and athletes.[5]


See also

References

  1. ^ "Sustanon 250, solution for injection". Retrieved 2019-06-15.
  2. ^ "Discontinuation of Sustanon 100 (testosterone replacement therapy)". NeLM. Archived from the original on 29 September 2009. Retrieved 9 August 2016. {{cite web}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)
  3. ^ "Steroids and SARMS Handbook". Retrieved 2019-06-15.
  4. ^ "Pharmacological information. Sust 250 concept". 2018-06-19. Retrieved 2018-07-10.
  5. ^ "Steroids and SARMS Handbook". Retrieved 2019-06-15.


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