Mestanolone

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Mestanolone
Mestanolone.png
Systematic (IUPAC) name
(5α,17β)-17-hydroxy-17-methylandrostan-3-one
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy
category
  • US: X (Contraindicated)
Routes of
administration
Oral
Legal status
Legal status
Pharmacokinetic data
Bioavailability 99% oral
Protein binding yes
Metabolism Hepatic
Biological half-life ?
Excretion Renal
Identifiers
CAS Number 521-11-9 N
ATC code none
PubChem CID 10633
ChemSpider 10187 YesY
UNII S712YZ168E YesY
KEGG D01533 YesY
ChEMBL CHEMBL261514 YesY
Synonyms (5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one
Chemical data
Formula C20H32O2
Molar mass 304.467 g/mol
 NYesY (what is this?)  (verify)

Mestanolone (brand names Andoron, Notandron) is the 17α-methylated version of dihydrotestosterone (DHT).[1] The systematic name of mestanolone is: 17β-hydroxy-17α-methylandrost-3-one.[2] It is an orally bioavailable androgenic steroid that is highly androgenic while only slightly anabolic. It is incapable of aromatization and is not an agonist of the progesterone receptor.

Dosage Information

Dosages range from 10 mg to 30 mg a day for males. Women should avoid Mestanolone for it is very androgenic. Long term use, more than 12 weeks should be avoided do to hepatoxicity. Since Mestanolone is unable to convert to estrogen, it is very useful during cutting phases or when one wishes to avoid excess weight gain.

Synonyms

Mestanolone is also known as methylandrostanolone or 17alpha-methylandrostanolone.[3]

References[edit]

  1. ^ CTD (2007). "Chemicals: mestanolone". CTD - Comparative Toxicogenomics Database. Retrieved September 3, 2007. 
  2. ^ Biology Online.org (2007). "mestanolone". Biology Online.org. Retrieved September 3, 2007. 
  3. ^ "Compound Summary for CID 10633". Pubchem. Retrieved May 11, 2016.