6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by DferDaisy (talk | contribs) at 17:55, 19 October 2019 (corrected punctuation in reference). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide
Identifiers
  • 6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide
Chemical and physical data
FormulaC16H16ClN3O2
Molar mass317.769 g/mol g·mol−1
3D model (JSmol)
  • c3cccnc3NC(=O)N(c1cc2Cl)CCc1cc2OCC

6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide (CEPC) is a drug which acts as a potent and selective antagonist for the serotonin 5-HT2C receptor. In animal studies it was found to potentiate the conditioned place preference induced by low-dose amphetamine, demonstrating that 5-HT2C-mediated disinhibition of dopamine release can cause interactions with dopaminergic drugs.[1]

See also

References

  1. ^ McCorvy, John D.; Harland, Aubrie A.; Maglathlin, Rebecca; Nichols, David E. (7 November 2011). "A 5-HT2C receptor antagonist potentiates a low dose amphetamine-induced conditioned place preference". Neuroscience Letters. 505 (1): 10–13. doi:10.1016/j.neulet.2011.07.036. PMC 3213641. PMID 21827831.
Retrieved from "https://en.wikipedia.org/w/index.php?title=6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide&oldid=922060218"