PRX-03140

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PRX-03140
PRX-03140.svg
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
Formula C19H27N3O3S
Molar mass 377.501 g/mol
3D model (JSmol)

PRX-03140 is a partial agonist (18% relative to 5-HT[1]) of the 5-HT4 receptor that is being developed by EPIX Pharmaceuticals for Alzheimer's disease.[2]

References[edit]

  1. ^ Shen F, Smith JA, Chang R, et al. (2011). "5-HT(4) receptor agonist mediated enhancement of cognitive function in vivo and amyloid precursor protein processing in vitro: A pharmacodynamic and pharmacokinetic assessment". Neuropharmacology. 61 (1-2): 69–79. doi:10.1016/j.neuropharm.2011.02.026. PMID 21392515. 
  2. ^ Shen, F (August 2011). "5-HT(4) receptor agonist mediated enhancement of cognitive function in vivo and amyloid precursor protein processing in vitro: A pharmacodynamic and pharmacokinetic assessment". Neuropharmacology. 61 (1-2): 69–79. doi:10.1016/j.neuropharm.2011.02.026. PMID 21392515.