6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide

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6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide
CEPC structure.png
Identifiers
Chemical and physical data
FormulaC16H16ClN3O2
Molar mass317.769 g/mol g·mol−1
3D model (JSmol)

6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide (CEPC) is a drug which acts as a potent and selective antagonist for the serotonin 5-HT2C receptor. In animal studies it was found to potentiate the conditioned place preference induced by low-dose amphetamine, demonstrating that 5-HT2C-mediated disinhibition of dopamine release can cause interactions with dopaminergic drugs.[1]

See also[edit]

References[edit]

  1. ^ McCorvy, John D.; Harland, Aubrie A.; Maglathlin, Rebecca; Nichols, David E. (7 November 2011). "A 5-HT2C receptor antagonist potentiates a low dose amphetamine-induced conditioned place preference". Neuroscience Letters. 505 (1): 10–13. doi:10.1016/j.neulet.2011.07.036. PMC 3213641. PMID 21827831.