KML-010

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KML-010
KML-010 structure.png
Identifiers
PubChem CID
ChemSpider
Chemical and physical data
Formula C18H24FN3O2
Molar mass 333.400 g/mol
3D model (JSmol)
  (verify)

KML-010 is a drug derived from spiperone. It functions as a highly selective 5-HT2A receptor antagonist, with negligible affinity for the 5-HT1A or 5-HT2C receptors, and over 400-fold lower affinity for the D2 receptor in comparison to spiperone.[1]

See also[edit]

References[edit]

  1. ^ Glennon RA, Metwally K, Dukat M, Ismaiel AM, De los Angeles J, Herndon J, Teitler M, Khorana N (June 2002). "Ketanserin and spiperone as templates for novel serotonin 5-HT(2A) antagonists". Current Topics in Medicinal Chemistry. 2 (6): 539–58. doi:10.2174/1568026023393787. PMID 12052193.