Androgen ester
From Wikipedia, the free encyclopedia
This is an old revision of this page, as edited by 1.128.109.156 (talk) at 13:39, 5 April 2018 (Changed estrogen to testosterone). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.
An androgen or anabolic steroid ester is an ester of an androgen/anabolic steroid (AAS) such as the natural testosterone or dihydrotestosterone (DHT) or the synthetic nandrolone (19-nortestosterone). Esterification renders AAS into metabolism-resistant prohormones of themselves, improving oral bioavailability, increasing lipophilicity, and extending the terminal half-life (which necessitates less frequent administration). In addition, with intramuscular injection, AAS esters are absorbed more slowly into the body, further improving the terminal half-life. Aside from differences in pharmacokinetics (e.g., duration), these esters essentially have the same effects as the parent drugs.[1] They are used in androgen replacement therapy (ART), among other indications. Examples of androgen esters include the testosterone esters testosterone cypionate, testosterone enanthate, testosterone propionate, and testosterone undecanoate and the nandrolone esters nandrolone decanoate and nandrolone phenylpropionate.
See also
- List of androgen esters
- List of androgens/anabolic steroids
- Steroid ester
- Estrogen ester
- Progestogen ester
References
- ^ Richard Lawrence Miller (2002). The Encyclopedia of Addictive Drugs. Greenwood Publishing Group. pp. 416–. ISBN 978-0-313-31807-8.
Further reading
- Vermeulen A (1975). "Longacting steroid preparations". Acta Clin Belg. 30 (1): 48–55. doi:10.1080/17843286.1975.11716973. PMID 1231448.
| ARTooltip Androgen receptor |
| ||||||
|---|---|---|---|---|---|---|---|
| GPRC6A |
| ||||||