Interleukin 28 receptor, alpha subunit

IFNLR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3OG4, 3OG6, 5IXI, 5IXD
Identifiers
Aliases	IFNLR1, CRF2/12, IFNLR, IL-28R1, IL28RA, LICR2, Interleukin 28 receptor, alpha subunit, interferon lambda receptor 1
External IDs	OMIM: 607404; MGI: 2429859; HomoloGene: 52086; GeneCards: IFNLR1; OMA:IFNLR1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	24,187,959 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	135,435,492 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; jejunal mucosa; ; buccal mucosa cell; ; right lobe of liver; ; testicle; ; mucosa of sigmoid colon; ; cerebellar vermis; ; duodenum; ; cerebellar hemisphere; ; lymph node;
	Top expressed in
	granulocyte; ; urethra; ; jejunum; ; transitional epithelium of urinary bladder; ; middle ear; ; lip; ; ileum; ; duodenum; ; esophagus; ; Hindgut;
	More reference expression data
	n/a
Gene ontology
Molecular function	cytokine receptor activity; protein binding;
Cellular component	integral component of membrane; interleukin-28 receptor complex; membrane; plasma membrane;
Biological process	response to type III interferon; mucosal immune response; defense response to virus; negative regulation of cell population proliferation; regulation of defense response to virus by host; cytokine-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	163702
	242700
	ENSG00000185436
	ENSMUSG00000062157
	Q8IU57
	Q8CGK5
	NM_170743; NM_173064; NM_173065
	NM_174851
	NP_734464; NP_775087; NP_775088
	NP_777276
	Wikidata
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