From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
NESS-040C5 structure.png
Clinical data
ATC code
  • none
Legal status
Legal status
CAS Number
CompTox Dashboard (EPA)
Chemical and physical data
Molar mass447.64 g·mol−1
3D model (JSmol)

NESS-040C5 is a potent cannabinoid agonist which was developed for the treatment of glaucoma.[1] It has reasonable selectivity for the CB2 receptor subtype, having a CB2 affinity of 0.4nM, and 25x selectivity over the related CB1 receptor.[2]

See also[edit]


  1. ^ Paolo Lazzari et al. Pharmaceutical Compounds. US Patent 8106218
  2. ^ Hanus LO, Mechoulam R (2010). "Novel natural and synthetic ligands of the endocannabinoid system". Current Medicinal Chemistry. 17 (14): 1341–59. doi:10.2174/092986710790980096. PMID 20166928.