From Wikipedia, the free encyclopedia
Jump to: navigation, search
O-1871 structure.png
Systematic (IUPAC) name
Clinical data
Legal status
  • Banned as cyclohexylphenol derivative (US, UK)
CAS Registry Number 620964-96-7
ATC code None
PubChem CID: 10405368
ChemSpider 8580806
Chemical data
Formula C23H38O2
Molecular mass 346.55 g/mol

O-1871 is a potent cannabinoid agonist which was invented by Billy R Martin and Raj K Razdan in 2002. It has a CB1 receptor affinity of 2.0nM and a CB2 receptor affinity of 0.3nM.[1] Structurally, O-1871 is a cyclohexylphenol derivative related to CP 47,497, and so is illegal in most jurisdictions where CP 47,497 and its derivatives are banned. However the 3,3-dimethylcyclohexyl substituent of O-1871 can be replaced by various other groups, producing other potent compounds such as the cycloheptyl derivative O-1656 and the 2-adamantyl derivative O-1660, as well as the corresponding 3,5-dichlorophenyl derivative,[2] which are not cyclohexylphenol derivatives.

See also[edit]