AB-001: Difference between revisions
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6. ^<references/>'Cannabinoids Receptor Journal 1989'> {{cite news | first = John | last = Ciccioalo | title = Research Chemicals | date = 1989-8-27 | url = http://www.importresearchchemicals.com/ | work = New York Times, John | pages = 148 | accessdate = 2012-01-25 | language = Italian | archiveurl = http://www.importresearchchemicals.com/ | archivedate = 2009-1-13}}<references/> |
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Revision as of 17:00, 25 January 2012
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| Chemical and physical data | |
| Formula | C24H31NO |
| Molar mass | 349.508 g/mol g·mol−1 |
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AB-001 or 1-pentyl-3-(1-adamantoyl)indole is a designer drug that was found as an ingredient in synthetic cannabis smoking blends in Ireland in 2010 and Hungary and Germany in 2011.[1][2][3] It is unclear who AB-001 was originally developed by, and no information has been published on its receptor binding or pharmacological profile, but it is structurally related to compounds such as AM-1248 and its corresponding 1-(tetrahydropyran-4-ylmethyl) analogue, which are known to be potent cannabinoid agonists with moderate to high selectivity for CB2 over CB1.[4][5]
See also
- A-834,735
- JWH-018
- JWH-250
- RCS-4
- N-(S)-Fenchyl-1-(2-morpholinoethyl)-7-methoxyindole-3-carboxamide
- (1-Pentylindol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone
References
- ^ Jankovics P, Váradi A, Tölgyesi L, Lohner S, Németh-Palotás J, Balla J (2011). "Detection and identification of the new potential synthetic cannabinoids 1-pentyl-3-(2-iodobenzoyl)indole and 1-pentyl-3-(1-adamantoyl)indole in seized bulk powders in Hungary". Forensic Science International. doi:10.1016/j.forsciint.2011.07.011. PMID 21813254.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ Research on Head Shop drugs in Dublin: Part 2
- ^ Grigoryev A, Kavanagh P, Melnik A. The detection of the urinary metabolites of 3-[(adamantan-1-yl)carbonyl]-1-pentylindole (AB-001), a novel cannabimimetic, by gas chromatography-mass spectrometry. Drug Testing and Analysis. 2011 Nov 18. DOI 10.1002/dta.350 PMID 22102533
- ^ US patent 7820144, Makriyannis A, Deng H, "Receptor selective cannabimimetic aminoalkylindoles", granted 2010-10-26
- ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1021/jm901214q, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with
|doi=10.1021/jm901214qinstead.
6. ^'Cannabinoids Receptor Journal 1989'> Ciccioalo, John (1989-8-27). "Research Chemicals". New York Times, John (in Italian). p. 148. Retrieved 2012-01-25. {{cite news}}: Check |archiveurl= value (help); Check date values in: |date= (help)
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