CP-135807

CP-135807
Identifiers
	IUPAC name 3-([(2R)-1-methylpyrrolidin-2-yl]methyl)-N-(3-nitropyridin-2-yl)-1H-indol-5-amine;
CAS Number	151272-90-1 ;
PubChem CID	5487088;
ChemSpider	4589207;
UNII	TE348FQ6DA;
ChEMBL	ChEMBL80913;
CompTox Dashboard (EPA)	DTXSID10164748 ;
ECHA InfoCard	100.189.849
Chemical and physical data
Formula	C19H21N5O2
Molar mass	351.410 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1CCC[C@@H]1Cc2c[nH]c3c2cc(cc3)Nc4c(cccn4)[N+](=O)[O-];
	InChI InChI=1S/C19H21N5O2/c1-23-9-3-4-15(23)10-13-12-21-17-7-6-14(11-16(13)17)22-19-18(24(25)26)5-2-8-20-19/h2,5-8,11-12,15,21H,3-4,9-10H2,1H3,(H,20,22)/t15-/m1/s1; Key:YPFIYPNOWVPAPR-OAHLLOKOSA-N;
	(verify)

CP-135807 is a drug which acts as a potent and selective agonist for the 5-HT_1D serotonin receptor, and is used to study the function of this receptor subtype.^[1]^[2]

References

^ Mansbach RS, Rovetti CC, Macor JE (December 1996). "CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon". Psychopharmacology. 128 (3): 313–9. doi:10.1007/s002130050139. PMID 8972551. S2CID 19376926.
^ Hertel P, Nomikos GG, Svensson TH (August 1999). "The antipsychotic drug risperidone interacts with auto- and hetero-receptors regulating serotonin output in the rat frontal cortex". Neuropharmacology. 38 (8): 1175–84. doi:10.1016/S0028-3908(99)00045-3. PMID 10462130. S2CID 33060351.

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[pmid8972551-1] Mansbach RS, Rovetti CC, Macor JE (December 1996). "CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon". Psychopharmacology. 128 (3): 313–9. doi:10.1007/s002130050139. PMID 8972551. S2CID 19376926.

[pmid10462130-2] Hertel P, Nomikos GG, Svensson TH (August 1999). "The antipsychotic drug risperidone interacts with auto- and hetero-receptors regulating serotonin output in the rat frontal cortex". Neuropharmacology. 38 (8): 1175–84. doi:10.1016/S0028-3908(99)00045-3. PMID 10462130. S2CID 33060351.

[1]

[2]

See also

References