Bromazine

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Not to be confused with Promazine.
Bromazine
Clinical data
MedlinePlusa682065
Routes of
administration		Oral
ATC code
Pharmacokinetic data
BioavailabilityHigh
Protein binding96%
MetabolismMostly hepatic (CYP-mediated), also renal
Elimination half-life1 to 4 hours
Identifiers
  • 2-[(4-Bromophenyl)-phenylmethoxy]-N,N-dimethylethanamine
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.003.854 Edit this at Wikidata
Chemical and physical data
FormulaC17H20BrNO
Molar mass334.257 g·mol−1
3D model (JSmol)
  • Brc1ccc(cc1)C(OCCN(C)C)c2ccccc2
  • InChI=1S/C17H20BrNO/c1-19(2)12-13-20-17(14-6-4-3-5-7-14)15-8-10-16(18)11-9-15/h3-11,17H,12-13H2,1-2H3 checkY
  • Key:NUNIWXHYABYXKF-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Bromazine (trade names Ambodryl,[1] Ambrodil and others), also known as bromodiphenhydramine, is an antihistamine and anticholinergic.[2] It is a brominated form of diphenhydramine.

References

  1. ^ Baker, Charles E. (1974). Physicians' Desk Reference (28 ed.). Oradell, NJ 07649: Medical Economics Company. pp. 1076, 1081. {{cite book}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)CS1 maint: location (link)
  2. ^ Maclaren WR, Bruff WC, Eisenberg BC, Weiner H, Martin WH (1955). "A clinical comparison of carbinoxamine maleate, tripelennamine hydrochloride, and bromodiphenhydramine hydrochloride in treating allergic symptoms". Annals of Allergy. 13 (3): 307–12. PMID 14377226.
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