David Baltimore: Difference between revisions
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Revision as of 20:58, 1 September 2014
David Baltimore | |
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Born | New York City, New York, USA | March 7, 1938
Nationality | United States |
Alma mater | Swarthmore College Rockefeller University |
Known for | Reverse transcriptase Baltimore classification |
Spouse | Alice S. Huang (m. 1968; 1 child) |
Awards | NAS Award in Molecular Biology (1974) Nobel Prize in Physiology or Medicine (1975) |
Scientific career | |
Fields | Biology |
Institutions | Massachusetts Institute of Technology Rockefeller University California Institute of Technology |
David Baltimore (born March 7, 1938) is an American biologist, university administrator, and Nobel laureate in Physiology or Medicine. He served as president of the California Institute of Technology (Caltech) from 1997 to 2006, and is currently the President Emeritus and Robert Andrews Millikan Professor of Biology at Caltech. He also served as president of Rockefeller University from 1990 to 1991, and was president of the American Association for the Advancement of Science in 2007. Dr. Baltimore has profoundly influenced international science, including key contributions to immunology, virology, cancer research, biotechnology, and recombinant DNA research, through his accomplishments as a researcher, administrator, educator, and public advocate for science and engineering. He was awarded the U.S. National Medal of Science in 1999. [1]
Biography
Early years
Baltimore was born to Gertrude (Lipschitz) and Richard Baltimore in New York City. Raised in the Queens neighborhoods of Forest Hills and Rego Park, Queens, he moved with his family to suburban Great Neck, New York while he was in second grade because his mother felt that the city schools were inadequate. His father had been raised as an Orthodox Jew and his mother was an atheist, and Baltimore observed Jewish holidays and would attend synagogue with his father through his Bar Mitzvah.[2] He graduated from Great Neck High School in 1956, and credits his interest in biology to a high-school summer spent at the Jackson Laboratory's Summer Student Program in Bar Harbor, Maine.[3][4] He earned a BA at Swarthmore College in 1960, and received his Ph.D. at Rockefeller University in 1964. After postdoctoral fellowships at Massachusetts Institute of Technology (MIT) and Albert Einstein College of Medicine and a non-faculty research position at the Salk Institute, he joined the MIT faculty in 1968. He was elected a Fellow of the American Academy of Arts and Sciences in 1974.[5]
Career
In 1975, at the age of 37, he shared the Nobel Prize for Physiology or Medicine with Howard Temin and Renato Dulbecco. The citation reads, "for their discoveries concerning the interaction between tumor viruses and the genetic material of the cell." At the time, Baltimore's greatest contribution to virology was his discovery of reverse transcriptase (RTase or RT). Reverse transcriptase is essential for the reproduction of retroviruses such as HIV and was also discovered independently, and at about the same time, by Mizutani and Temin.[6]
Also in 1975, Baltimore was an organizer of the Asilomar conference on recombinant DNA. In 1982, Baltimore was appointed the founding director of MIT's Whitehead Institute, where he remained through June 1990.
In 1981, Baltimore and Vincent Racaniello, a post-doctoral fellow in his laboratory, used recombinant DNA technology to generate a plasmid encoding the genome of poliovirus, an animal RNA virus. The plasmid DNA was introduced into cultured mammalian cells and infectious poliovirus was produced.[7] The infectious clone, DNA encoding the genome of a virus, is a standard tool used today in virology. Other important breakthroughs from Baltimore's lab include the discovery of the transcription factor NF-κB and the recombination activating genes RAG-1 and RAG-2.
Baltimore became president of Rockefeller University in New York City on July 1, 1990. After resigning on December 3, 1991, Baltimore remained on the Rockefeller University faculty and continued research until spring of 1994. He then rejoined the MIT faculty.
Baltimore has influenced national policy concerning recombinant DNA research and the AIDS epidemic. He has trained many doctoral students and postdoctoral fellows, several of whom have gone on to notable and distinguished research careers. Baltimore is a member of The Jackson Laboratory's Board of Trustees, the Bulletin of the Atomic Scientists' Board of Sponsors, the National Academy of Sciences USA (NAS), the NAS Institute of Medicine (IOM), Amgen, Inc. Board of Directors, the BB Biotech AG Board of Directors, the National Institutes of Health (NIH) AIDS Vaccine Research Committee (AVRC), and numerous other organizations and their boards.
Baltimore is a member of the USA Science and Engineering Festival's Advisory Board[8] and the Pontifical Academy of Sciences
Imanishi-Kari case
During the late 1980s and early 1990s, Thereza Imanishi-Kari, a scientist who was not in Baltimore's laboratory but in a separate, independent laboratory at MIT, was implicated in a case of scientific fraud. The case received extensive news coverage and a Congressional investigation. The case was linked to Baltimore's name because of his scientific collaboration with and later his strong defense of Imanishi-Kari against accusations of fraud.
In 1986, while a Professor of Biology at MIT and Director at Whitehead, Baltimore co-authored a scientific paper on immunology with Thereza Imanishi-Kari (an Assistant Professor of Biology who had her own laboratory at MIT) as well as four others.[9] A postdoctoral fellow in Imanishi-Kari's laboratory, Margot O'Toole, who was not an author, reported concerns about the paper, ultimately accusing Imanishi-Kari of fabricating data in a cover-up. Baltimore, however, refused to retract the paper.
O'Toole soon dropped her challenge, but the NIH, which had funded the contested paper's research, began investigating, thanks to the insistence of Walter W. Stewart, a self-appointed fraud buster, and Ned Feder, his lab head at the NIH.[10] Representative John Dingell (D-MI) also aggressively pursued it, eventually calling in U.S. Secret Service (USSS; U.S. Treasury) document examiners.[11]
Around October 1989, when Baltimore was appointed president of Rockefeller University, around a third of the faculty opposed his appointment because of concerns about his behaviour in the Imanishi-Kari case. He had to visit every laboratory, one by one, to hear those concerns directly from each group of researchers.[10]
In a draft report dated March 14, 1991 and based mainly on USSS forensics findings, NIH's fraud unit, then called the Office of Scientific Integrity (OSI), accused Imanishi-Kari of falsifying and fabricating data. It also criticized Baltimore for failing to embrace O'Toole's challenge.[citation needed] Less than a week later, the report was leaked to the press.[12] Baltimore and three co-authors then retracted the paper; Imanishi-Kari and Moema H. Reis did not sign the retraction.[13] In the report, Baltimore admitted that he was "too willing to accept" Imanishi-Kari's explanations, and felt he "did too little to seek an independent verification of her data and conclusions."[14] Baltimore publicly apologized for not taking a whistle-blower's charge seriously.[15]
Amid concerns raised by negative publicity in connection with the scandal, Baltimore resigned as president of Rockefeller University[16] and rejoined the MIT Biology faculty.[17]
In July 1992, the US Attorney for the District of MD, who had been investigating the case, announced he would bring neither criminal nor civil charges against Imanishi-Kari.[18] In October 1994, however, OSI's successor, the Office of Research Integrity (ORI; HHS) found Imanishi-Kari guilty on 19 counts of research misconduct, basing its conclusions largely on Secret Service analysis of laboratory notebooks.
An HHS appeals panel began meeting in June 1995 to review all charges in detail. In June 1996, the panel ruled that the ORI had failed to prove even one of its 19 charges. After throwing out much of the documentary evidence gathered by the ORI, the panel dismissed all charges against Imanishi-Kari. As their final report stated, the HHS panel "found that much of what ORI presented was irrelevant, had limited probative value, was internally inconsistent, lacked reliability or foundation, was not credible or not corroborated, or was based on unwarranted assumptions." It did conclude that "The Cell paper as a whole is rife with errors of all sorts ... [including] some which, despite all these years and layers of review, have never previously been pointed out or corrected. Responsibility ... must be shared by all participants." Neither OSI nor ORI ever accused Baltimore of research misconduct.[19][20] The reputations of Stewart and Feder, who had pushed for the investigation, were very damaged.[20]
Baltimore has been both defended and criticized for his actions in this matter.[21][22][23][24][25][26][27] In 1993, Yale University mathematician Serge Lang strongly criticized Baltimore's behavior.[28] Historian of science Daniel Kevles, writing after the exoneration of Imanishi-Kari, recounted the affair in his 1998 book, The Baltimore Case.[29][30] Horace Freeland Judson also gives a critical assessment of Baltimore's actions in The Great Betrayal: Fraud In Science.[31] Baltimore has also written his own analysis.[32]
Caltech
On May 13, 1997, Baltimore was appointed president of the California Institute of Technology (Caltech).[33] He began serving in the office 15 October 1997 and was inaugurated 9 March 1998.[34]
During Baltimore's tenure at Caltech, United States President Bill Clinton awarded Baltimore the National Medal of Science in 1999 for his numerous contributions to the scientific world. In 2004, Rockefeller University gave Baltimore its highest honor, Doctor of Science (honoris causa).[35]
In October 2005, Baltimore resigned the office of the president,[36] saying, "This is not a decision that I have made easily, but I am convinced that the interests of the Institute will be best served by a presidential transition at this particular time in its history..."[37] Former Georgia Tech Provost Jean-Lou Chameau succeeded Baltimore as president of Caltech.[38] Baltimore remains the Millikan Professor of Biology at Caltech and is an active member of the Institute's community.
Soon after Baltimore's resignation, and at his request, Caltech began investigating the work Luk van Parijs had conducted while a postdoc in Baltimore's laboratory.[39] Van Parijs first came under suspicion at MIT, for work done after he had left Baltimore's lab. After van Parijs had been fired by MIT, his doctoral supervisor also noted problems with work van Parijs did at the Brigham and Women's Hospital, before leaving Harvard to go to Baltimore's lab.[40] Concluding in March 2007, the Caltech investigation found van Parijs alone committed research misconduct and that four papers co-authored by Baltimore, van Parijs, and others required correction.[41]
Academy Family at The Salk Institute (1965-1967)
Name | Years Working in the Lab | Position in Lab | Current Title | Institution |
---|---|---|---|---|
Dr. Marc Girard | 1966 - 1967 | Visiting Scientist | Retired | |
Dr. Michael Jacobson | 1967 - 1969 | Graduate Student | Executive Director | Center for Science in the Public Interest |
Dr. Alice Huang | 1968 - 1970 | PostDoc | Senior Faculty Associate | California Institute of Technology |
Academy Family at the MIT (1968-1982)
Name | Years Working in the Lab | Position in Lab | Current Title | Institution |
---|---|---|---|---|
Dr. Charles Cole, Jr. | 1968 - 1973 | Graduate Student, PostDoc | Principle Investigator | Dartmouth Medical School |
Dr. David Rekosh | 1968 - 1972 | Graduate Student | Professor | University of Virginia School of Medicine |
Dr. Martha Stampfer | 1968 - 1972 | Graduate Student | Senior Scientist | Lawrence Berkeley National Laboratory |
Dr. Kenneth Manly | 1969 - 1971 | PostDoc | Research Staff | Roswell Park Cancer Institute |
Dr. Robert Taber, Jr. | 1969 - 1972 | PostDoc | Emergency Physician | Lourdes Medical Center |
Dr. Ian Molineux | 1979 - 1972 | PostDoc | Professor in Molecular Genetics & Microbiology | The University of Texas At Austin |
Dr. Lydia Villa-Komaroff | 1970 - 1975 | Graduate Student | CSO | Cytonome, Inc |
Dr. Eckard Wimmer | 1970 - | Visiting Professor | Distinguish Professor | Stony Brook University |
Dr. Hung Y. Fan | 1971 - 1973 | PostDoc | Professor | U.C. Irvine |
Dr. Naomi Guttman-Bass | 1971 - 1976 | Graduate Student | Professor | Hebrew University |
Dr. Deborah Spector | 1971 - 1975 | Graduate Student | Principle Investigator | U.C. San Diego |
Dr. Inder M. Verma | 1971 - 1974 | PostDoc | Professor | The Salk Institute |
Dr. Peter Besmer | 1972 - 1980 | PostDoc | Faculty | Memorial Sloan-Kettering Cancer Center |
Dr. Ellen Rothenberg | 1972 - 1977 | Graduate Student | Professor | California Institute of Tecchnology |
Dr. William Haseltine | 1973 - 1976 | PostDoc | Chairman and President | The Access Health International |
Dr. Martinez Hewlett | 1973 - 1976 | PostDoc | Professor | The University of Arizona |
Dr. Nancy Hopkins | 1973 - 1974 | PostDoc | Professor | Massachusetts Institute of Technology |
Dr. Paul Jolicoeur | 1973 - 1976 | PostDoc | Professor | The Clinical Research Institute of Montreal |
Dr. David Knipe | 1973 - 1976 | Graduate Student | Professor | Harvard Medical School |
Dr. Ronald P. McCaffrey | 1973 - 1977 | Visiting Scientist | Retired | |
Dr. Amos Panet | 1973 - | PostDoc | Professor | The Hebrew University |
Dr. Naomi Rosenberg | 1973 - 1980 | PostDoc | Professor | Tufts University School of Medicine |
Dr. Patrick Chung-Shu Kung | 1974 - 1977 | PostDoc | CSO | The T-Cell Sciences |
Dr. Udy Olshevsky | 1974 - 1976 | PostDoc | Researcher | Israel Institute for Bio. Research |
Dr. Paula Traktman | 1974 - 1981 | Graduate Student | Professor | The Medical College of Wisconsin |
Dr. James Flanegan | 1975 - 1978 | PostDoc | Professor | University of Florida |
Dr. Victor Ambros | 1976 - 1979 | Graduate Student | Professor | University of Massachusetts |
Dr. Alfred Bothwell | 1976 - 1982 | PostDoc | Professor | Yale Medical School |
Dr. Vincenzo Enea | 1976 - 1979 | PostDoc | Director of Preclinical Affairs | The Enzo Therapeutics, Inc. |
Dr. Ralf Filip Pettersson | 1976 - 1978 | PostDoc | Director of the Stockholm Branch | The Ludwig Institute for Cancer Research |
Dr. John K. Rose | 1976 - 1978 | PostDoc | Professor | Yale University School of Medicine |
Dr. Anthony Shield | 1976 - 1979 | Graduate Student | Professor | The Karmanos Cancer Institute |
Dr. Edward Siden | 1976 - 1980 | PostDoc | Professor | Mount Sinai School of Medicine |
Dr. Owen N. Witte | 1976 - 1980 | PostDoc | Principle Investigator | The Howard Hughes Medical Institute/UCLA |
Dr. Frederick Alt | 1977 - 1982 | PostDoc | Principle Investigator | The Children's Hospital |
Dr. Eli Gilboa | 1977 - 1980 | PostDoc | Professor | Duke University |
Dr. Lennart Philipson | 1977 - 1978 | visiting Professor | Professor | The Skirball Institute |
Dr. Leland F. Velicer | 1977 - 1978 | Visiting Sccientist | Professor | Michigan State University |
Dr. Margaret Baron | 1978 - 1981 | Graduate Student | Professor | The Mount Sinai School of Medicine |
Dr. Nigel Crawford | 1978 - 1984 | Graduate Student | Professor | U.C. San Diego |
Dr. Asim Dasgupta | 1978 - 1981 | PostDoc | Professor | U.C. Los Angeles |
Dr. Douglas Faller | 1978 - 1979 | PostDoc | Professor | Boston University |
Dr. Stephen Goff | 1978 - 1981 | PostDoc | Professor | Howard Hughes Medical Institute |
Dr. Sudha W. Mitra | 1978 - 1981 | PostDoc | Researcher | Merck Research Labs |
Dr. Susanna Lewis | 1979 - 1985 | Graduate Student | Sr. Scientist | The Hospital for Sick Children Research Institute |
Dr. Vincent Racaniello | 1979 - 1982 | PostDoc | Professor | Columbia University |
Dr. Varda Rotter | 1979 - 1981 | PostDoc | Professor | The Weizmann Institute of Science |
Dr. Charles B. Shoemaker | 1979 - 1981 | PostDoc | Professor | Tufts University School of Veterinary Medicine |
Dr. Michael Boss | 1980 - 1982 | PostDoc | Chief Business Officer | The Xanthus Pharmaceuticals, Inc. |
Dr. James Champoux | 1980 - 1981 | Visiting Scientist | Professor | University of Washington |
Dr. Marie Chow | 1980 - 1985 | PostDoc | Professor | University of Arkansas |
Dr. Dennis Loh | 1980 - 1984 | PostDoc | Principle Investigator | The Hoffman-La Roche Inc. |
Dr. Richard Mulligan | 1980 - 1981 | PostDoc | co-Chief | The Children's Hospital |
Dr. Ron Prywes | 1980 - 1984 | Graduate Student | Professor | Columbia University |
Dr. Jean Yin Jen Wang | 1980 - 1983 | PostDoc | Associate Director of Basic Research | U.C. San Diego School of Medicine |
Dr. Stephen Desiderio | 1981 - 1984 | PostDoc | Professor | Johns Hopkins University School of Medicine |
Dr. J. Gordon Foulkes | 1981 - 1984 | PostDoc | Managing Director | The Rivervest Ventures |
Dr. Yoram Groner | 1981 - 1982 | Visiting Scientist | Principle Investigator | The Weizmann Institute |
Dr. Fred D. Ledley | 1981 - 1983 | PostDoc | Director at Center for Integration of Science and Industry | Bentley University |
Dr. Cary Queen | 1981 - 1982 | PostDoc | President | The Galaxy Biotech |
Dr. Douglas Rice | 1981 - 1984 | PostDoc | Professor | Duke University Medical Center |
Dr. Nancy Andrews | 1982 - 1985 | Graduate Student | Dean and Vice Chancellor | Duke University |
Dr. Yehudit Bergman | 1982 - 1984 | PostDoc | Professor | Hebrew University |
Dr. Harris Bernstein | 1982 - 1987 | Graduate Student | Principle Investigator | NIDDK, National Institutes of Health |
Dr. Rudolf Grosschedl | 1982 - 1986 | PostDoc | Professor | The Max Planck Institute of Immunobiology and Epigentics, Freiburg |
Dr. Ned Landau | 1982 - 1986 | Graduate Student | Professor | The New York University School of Medicine |
Dr. Richard mann | 1982 - 1986 | Graduate Student | Professor | Columbia University |
Dr. Peter Sarnow | 1982 - 1986 | PostDoc | Professor | Stanford University |
Dr. Ranjan Sen | 1982 - 1986 | PostDoc | Sr. Investigator | NIA, National Institutes of Health |
Dr. Nancy Speck | 1982 - 1986 | PostDoc | Principle Investigator | UPenn |
Dr. Tai Te Wu | 1982 - | visiting Scientist | Professor | Northwestern University |
Academy Family at the Whitehead Institute (1983-1989)
Name | Years Working in the Lab | Position in Lab | Current Title | Institution |
---|---|---|---|---|
Dr. Yinon Ben-Neria | 1983 - 1986 | PostDoc | Professor | Hebrew University |
Dr. Karla Kirkegaard | 1983 - 1986 | PostDoc | Professor | Stanford University |
Dr. Bernard Mathey-Prevot | 1983 - 1987 | PostDoc | Professor | Duke University School of Medicine |
Dr. Shiv Pillai | 1983 - 1988 | PostDoc | Professor | Massachusetts General Hospital Cancer Center |
Dr. David Weaver | 1983 - 1987 | PostDoc | Professor | Harvard Medical School |
Dr. Jonathan Braun | 1984 - 1985 | PostDoc | Professor | U.C.L.A. School of Medicine |
Dr. Dan Silver | 1984 - 1992 | Graduate Student | Professor | Dana Farber Cancer Institute |
Dr. Louis Staudt | 1984 - 1988 | PostDoc | Principle Investigator | NCI, National Institutes of Health |
Dr. Andre Bernards | 1985 - 1988 | PostDoc | Professor | Massachusetts General Hospital Cancer Center |
Dr. Brygida Bersse | 1985 - 1988 | PostDoc | Professor | Boston University |
Dr. George Daley | 1985 - | Garduate Student | Professor | Harvard Medical School |
Dr. Peter Jackson | 1985 - 1990 | Graduate Student | Professor | Genentech, Inc. |
Dr. Michael Lenardo | 1985 - 1989 | PostDoc | Principle Investigator | NIAID, National Institutes of Health |
Dr. Ricardo Martinez | 1985 - 1989 | PostDoc | Sr. Research Advisor | Eli Lilly and Company |
Dr. Gary Nabel | 1985 - 1987 | visiting Scientist | Director | VRC, NIAID, National Institutes of Health |
Dr. Jacqueline Pierce | 1985 - 1989 | PostDoc | Drug Development Program Manager | Millennium Pharmaceuticals |
Dr. David Schtz | 1985 - 1991 | Graduate Student | Professor | Yale University Medicine School |
Dr. Allen Silverstone | 1985 - 1992 | visiting Scientist | Professor | State University of NY, Upstate Medical Center |
Dr. Nahum Sonenberg | 1985 - 1986 | Visiting Scientist | Professor | McGill University |
Dr. David Parker | 1986 - 1987 | Visiting Scientist | Professor | Oregon Health Sciences University |
Dr. Maggie Rosa | 1986 - | Visiting Scientist | Professor | Gloucester Education Foundation |
Dr. Didier Trono | 1986 - 1990 | PostDoc | Professor | EOFC |
Dr. Mark Feinberg | 1987 | PostDoc | VP | Merck Vaccines and Infectious Diseases |
Dr. Cornelis Murre | 1987 - 1990 | PostDoc | Professor | U.C. San Diego |
Dr. Marjorie Oettinger | 1987 | Graduate Student | Professor | Massachusetts General Hospital |
Dr. Anna Voronova | 1987 - 1991 | PostDoc | Consultant | AV Consulting, LLC |
Dr. Takashi Fujita | 1988 - 1993 | PostDoc | Professor | Laboratory of molecular Genetics |
Dr. Mark Schlissel | 1988 - 1991 | PostDoc | Professor | U.C. Berkeley |
Dr. Sankar Ghosh | 1989 - 1991 | PostDoc | Professor | Yale University Medical School |
Dr. Hsiou-Chi Liou | 1989 | PostDoc | Professor | Weill Medical College of Cornell University |
Dr. Patrick Matthias | 1989 | PostDoc | Professor | Friedrick Miescher Institute for Biomedical Research |
Dr. Garry Nolan | 1989 - 1993 | PostDoc | Professor | Stanford University |
Dr. Roger Pomerantz | 1989 - 1990 | Visiting Scientist | Professor | Thomas Jefferson University |
Dr. Kalle Saksela | 1989 | PostDoc | Professor | University of Helsinki |
Dr. Martin Scott | 1989 - 1997 | PostDoc | Senior Research Fellow | Merck |
Academy Family at the Rockefeller foundation (1990-1993)
Name | Years Working in the Lab | Position in Lab | Current Title | Institution |
---|---|---|---|---|
Dr. Bruce Mayer | 1990 - 1993 | PostDoc | Professor | University of Connecticut Health Center |
Dr. Warren Pear | 1991 - 1996 | PostDoc | Professor | UPenn |
Dr. Amer Beg | 1992 - 1996 | PostDoc | Professor | L. Lee Moffitt Cancer Center & Research Institute at USF |
Dr. Ben Chen | 1992 - 1998 | Graduate Student | Professor | MIT |
Dr. Ruibao Cheng | 1992 - 1994 | PostDoc | Professor | U.C.L.A., Jonsson Comprehensive Cancer Center |
Dr. Christopher Roman | 1992 - 1998 | PostDoc | Professor | State University of NY, Brooklyn |
Dr. William Sha | 1992 - 1996 | PostDoc | Professor | U.C. Berkeley |
Dr. Bruce Horwitz | 1993 - 1996 | PostDoc | Professor | Brigham & Womens Hospital |
Academy Family at the Massachusetts Institute of Technology (1994-1996)
Name | Years Working in the Lab | Position in Lab | Current Title | Institution |
---|---|---|---|---|
Dr. Howard Chang | 1994 - 1998 | Graduate Student | Professor | Stanford University School of Medicine |
Dr. Kathy Collins | 1994 - 1998 | PostDoc | Professor | University of Michigan |
Dr. Joshy Jacob | 1994 - 1998 | PostDoc | Professor | Emory University |
Dr. Anthony Koleske | 1994 - 1998 | PostDoc | Professor | Yale University |
Dr. Yang Xu | 1994 - 1995 | PostDoc | Professor | U.C. San Diego |
Dr. Xiaolu Yang | 1994 - 1998 | PostDoc | Professor | UPenn |
Dr. Sara Cherry | 1995 - 2000 | Graduate Student | Professor | UPenn School of Medicine |
Dr. George Cohen | 1995 - 1999 | PostDoc | Professor | Harvard University |
Dr. Rajesh Gandhi | 1995 - 1999 | PostDoc | MD | Massachusetts General Hospital |
Dr. Ilana Stancovski | 1995 - 1999 | PostDoc | Director | Turio Ltd |
Dr. Eric Brown | 1996 - 2003 | PostDoc | Professor | UPenn School of Medicine |
Dr. Nir Hacohen | 1996 - 1998 | PostDoc | Professor | Harvard Medical School |
Dr. Alex Hoffmann | 1996 - 2003 | PostDoc | Professor | U.C. San Diego |
Dr. Roya Khosravi-Far | 1996 - 1999 | PostDoc | Professor | Harvard University Medical School |
Dr. Carlos Lois | 1996 - 2002 | PostDoc | Professor | MIT |
Dr. Joel Pomerantz | 1997 - 2003 | PostDoc | Professor | Johns Hopkins University School of Medicine |
Dr. Zhou SongYang | 1996 | PostDoc | Professor | Baylor University |
Academy Family at the California Institute of Technology (1997-2008)
Name | Years Working in the Lab | Position in Lab | Current Title | Institution |
---|---|---|---|---|
Dr. Luk Van Parijs | 1997 - 2000 | PostDoc | Professor | MIT |
Dr. Mollie Meffert | 1998 - 2004 | PostDoc | Professor | Johns Hopkins University |
Dr. Xiao-Geng Qin | 1998 - 2003 | PostDoc | Professor | University of Texas |
Dr. Mark Boldin | 1999 - 2008 | PostDoc | Professor | California Institute of Technology |
Dr. Thomas Leung | 1999 - 2005 | PostDoc | Resident in Dermatology | stanford University |
Dr. Wange Lu | 1999 - 2005 | PostDoc | Professor | KSC Keck School of Medicine |
Dr. Matthew Porteus | 1999 - 2003 | PostDoc | Professor | University of Texas Southwestern |
Dr. Lili Yang | 1999 - 2013 | PostDoc | Professor | Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research |
Dr. Rafael Casellas | 2002 - 2003 | Research | Sr. Investigator | NIAMS, National Institutes of Health |
Dr. Markus Covert | 2004 - 2006 | PostDoc | Professor | Stanford University |
Dr. Konstantin Taganov | 2004 - 2008 | PostDoc | Staff Scientist | EMD Millipore |
Dr. Xin Luo | 2005 - 2011 | PostDoc | Professor | Virginia Tech |
Dr. Ryan O'Connell | 2006 - 2011 | PostDoc | Professor | University of Utah |
Dr. Dinesh Rao | 2006 - 2011 | Graduate Student | Professor | David Geffen School of Medicine |
Dr. Jesse Bloom | 2007 - 2011 | PostDoc | Professor | Fred Hutchinson Cancer Research Center |
Dr. Aadel Chaudhuri | 2007 - 2011 | Graduate Student | Resident MD | Scripps Mercy Hospital |
Dr. Alex Sigal | 2007 | PostDoc | Professor | Kwazulu-Natal Research Institute for Tuberculosis & HIV |
Dr. Thomas Su | 2007 - 2009 | Visiting Scientist | MD, Dermatology | Private Practice of Michael Novak |
Dr. Kenneth Yu | 2007 - 2012 | Graduate Student | MD, Training | Keck School of Medicine, USC |
Dr. Daniel Kahn | 2008 - 2011 | Visiting Scientist | Professor | David Geffen School of Medicine, UCLA |
Dr. Param Ramakrishnan | 2008 - 2013 | PostDoc | Professor | Case Western Reserve University |
Dr. Alex So | 2008 | PostDoc | PostDoc Fellow | California Institute of Technology |
Geoffrey Lovely | 2008 | Graduate | Graduate Student | California Institute of Technology |
Dr. Michael Bethune | 2009 | PostDoc | PostDoc Fellow | California Institute of Technology |
Jocelyn Kim | 2009 | Graduate Student | Graduate Student | California Institute of Technology |
Dr. Jimmy Zhao | 2009 | PostDoc | Medical Student | David Geffen School of Medicine, UCLA |
Dr. Devdoot Majumdar | 2010 | PostDoc | PostDoc Fellow | California Institute of Technology |
Arnav Mehta | 2010 | Graduate Student | Graduate Student | California Institute of Technology |
Vanessa Jonsson | 2010 | Graduate Student | Graduate Student | California Institute of Technology |
Rachel Galimidi | 2010 | Graduate Student | Graduate Student | California Institute of Technology |
Dr. Shuai Jiang | 2012 | PostDoc | PostDoc Fellow | California Institute of Technology |
Dr. Mati Mann | 2012 | PostDoc | PostDoc Fellow | California Institute of Technology |
Dr. Rajan Kulkarni | 2012 | Visiting Scientist | Visiting Research Scholar | California Institute of Technology |
Dr. Alok Joglekar | 2013 | PostDoc | PostDoc Fellow | California Institute of Technology |
Personal life
Baltimore was married in 1968 to Dr. Alice S. Huang. They have one daughter.
See also
- History of RNA biology
- List of Jewish Nobel laureates
- List of RNA biologists
- Baltimore classification
- 73079 Davidbaltimore
References
- ^ http://www.researchamerica.org/baltimore_david
- ^ David Baltimore - Interviewed by Sara Lippincott; October - November 2009, California Institute of Technology. Accessed February 21, 2013. "But she was also committed to her family and to my father's right to have his religion, and we celebrated the major holidays, we fasted on Yom Kippur, and I walked with my father to the shul, which was a long walk from where we lived."
- ^ Nobel Prize autobiography. Nobelprize.org (1938-03-07). Retrieved on 2012-02-17.
- ^ Kerr, Kathleen. "They Began Here", Newsday. Accessed 23 Oct 2007. "David Baltimore, 1975 Nobel laureate and one of the nation's best-known scientists, is a good case in point. The 60-year-old Baltimore, who graduated from Great Neck High School in 1956..."
- ^ "Book of Members, 1780–2010: Chapter B" (PDF). American Academy of Arts and Sciences. Retrieved 9 May 2011.
- ^ Judson, Horace F (2003-10-20). "No Nobel Prize for Whining". New York Times. Retrieved 2007-08-03.
{{cite news}}
: Italic or bold markup not allowed in:|publisher=
(help) - ^ Racaniello V, Baltimore D (1981). "Cloned poliovirus complemenatry DNA is infectious in mammalian cells". Science. 214 (453): 916–919. Bibcode:1981Sci...214..916R. doi:10.1126/science.6272391. PMID 6272391.
- ^ Advisors. Usasciencefestival.org. Retrieved on 2012-02-17.
- ^ Weaver D, Reis MH, Albanese C, Costantini F, Baltimore D, Imanishi-Kari T (April 1986). "Altered repertoire of endogenous immunoglobulin gene expression in transgenic mice containing a rearranged mu heavy chain gene". Cell. 45 (2): 247–59. doi:10.1016/0092-8674(86)90389-2. PMID 3084104.
{{cite journal}}
: CS1 maint: multiple names: authors list (link) (Retracted, see [PMID 2032282]) - ^ a b Philip Weiss (29 October 1989), "Conduct Unbecoming?", New York Times
- ^ "Fraud in NIH Grant Programs," 12 April 1988; "Scientific Fraud," 4 & 9 May 1989; and "Scientific Fraud (Part 2)," 14 May 1990 (transcript includes 30 April 1990 hearing on R. Gallo's NIH lab)
- ^ Philip J. Hilts, "Crucial Data Were Fabricated In Report Signed by Top Biologist" (New York Times, 21 March 1991, pp. A1, B10)
- ^ Weaver D, Albanese C, Costantini F, Baltimore D (May 1991). "Retraction: altered repertoire of endogenous immunoglobulin gene expression in transgenic mice containing a rearranged mu heavy chain gene". Cell. 65 (4): 536. doi:10.1016/0092-8674(91)90085-D. PMID 2032282.
{{cite journal}}
: CS1 maint: multiple names: authors list (link) - ^ http://www.gatewaycoalition.org/files/gateway_project_moshe_kam/resource/DBCre/bosg6may91.html
- ^ http://articles.baltimoresun.com/1991-08-02/news/1991214028_1_hadley-scientific-misconduct-misconduct-cases
- ^ Hall SS (December 1991). "David Baltimore's final days". Science. 254 (5038): 1576–9. Bibcode:1991Sci...254.1576H. doi:10.1126/science.1749930. PMID 1749930. or here [1]
- ^ Natalie Angier, "Embattled Biologist Will Return to M.I.T." (New York Times, 19 May 1992, P. C5)
- ^ Malcolm Gladwell, "Prosecutors Halt Scientific Fraud Probe; Researcher Baltimore Claims Vindication, Plans to 'Unretract' Paper" (Washington Post, 14 July 1992, P. A3);
Hamilton DP (July 1992). "U.S. attorney decides not to prosecute Imanishi-Kari". Science. 257 (5068): 318. Bibcode:1992Sci...257..318H. doi:10.1126/science.1321499. PMID 1321499. - ^ 1996 HHS report exonerating Imanishi-Kari. Hhs.gov. Retrieved on 2012-02-17.
- ^ a b "The public skirmish over the reputations of Massachusetts Institute of Technology professor David Baltimore and Tufts University researcher Thereza Imanishi-Kari has been formally ended by a report deeply embarrassing to the government". Boston Globe. 1996.
- ^ Foreman, Judy (23 May 1988). "Baltimore Speaks Out on Disputed Study in Letter Sent to Colleagues Around the Nation; He Calls for Protection Against 'threats' to Scientific Freedom". Boston Globe. p. 31.
- ^ Larry Thompson, "Science Under Fire; Behind the Clash Between Congress and Nobel Laureate David Baltimore" (Washington Post "Health" journal, 5(19): 12–6 (9 May 1989))
- ^ "This spectacle of damaged reputation was not just unseemly, but difficult to reconcile with the 51-year-old Baltimore's prominence and achievements". NYT Magazine. 1989.
- ^ Foreman, J. (17 April 1991). "MIT Institute Used Funds Wrongly". Boston Globe. p. 1.
- ^ Horace Freeland Judson (2004). The Great Betrayal: Fraud in Science. Orlando: Harcourt.
- ^ Kevles, Daniel J. (May 27, 1996). "Annals of Science: The Assault on David Baltimore". New Yorker.
- ^ Trono D (2001). "Ahead of the Curve: David Baltimore's Life in Science". Nature Medicine. 7 (7): 767. doi:10.1038/89868.
- ^ Lang S (1993). "Questions of scientific responsibility: the Baltimore case". Ethics Behav. 3 (1): 3–72. doi:10.1207/s15327019eb0301_1. PMID 11653082.
- ^ Kevles, Daniel J. (1998). The Baltimore Case: A Trial of Politics, Science, and Character. New York: W.W. Norton. ISBN 0-393-31970-9.
- ^ Gunsalus, C.K. (21 January 1999). "Review of Kevles' "The Baltimore Case..."". New England Journal of Medicine. 340 (3): 242. doi:10.1056/nejm199901213400320.
- ^ Judson, Horace F. (2004). The Great Betrayal: Fraud in Science. New York: Harcourt. ISBN 978-0151008773.
- ^ David Baltimore, 1989 (updated 2003). Issues.org (2003-07-09). Retrieved on 2012-02-17.
- ^ Caltech Media Relations, "Nobel Prize-winning Biologist David Baltimore Named President of the California Institute of Technology," 13 May 1997, photos & links; Richard Saltus, "MIT Laureate to Lead Caltech: Baltimore Weathered Data Dispute", Boston Globe, 14 May 1997, p. A3; Robert Lee Hotz, "Prominent Biology Nobelist Chosen to Head Caltech; Controversial and outspoken scientist David Baltimore says his appointment reflects school's desire for bigger role in nation's scientific debates." Los Angeles Times, 14 May 1997, pp. A1, 22, 23; "A Luminary of Science for Caltech's Presidency; Nobelist Baltimore has the needed background and clout." LA Times, 15 May 1997, p. B8; R.L. Hotz, "Biomedicine's Bionic Man". LA Times Magazine, 28 September 1997, pp. 10–13, 34–5
- ^ Caltech Media Relations, "New Caltech President To Be Honored with Formal Inauguration, Birthday Festschrift," 23 February 1998
- ^ Bhattacharjee, Y. (25 June 2004). "The Balance of Justice". Science. 304 (5679): 1901. doi:10.1126/science.304.5679.1901a.
- ^ LATimes.com, "Caltech President Baltimore Announces Retirement," 3 October 2005; R.L. Hotz, "Caltech President Who Raised School's Profile to Step Down". LA Times, 4 October 2005, p. A1
- ^ Caltech Media Relations, "Baltimore to Retire as Caltech President; Will Remain at Institute as Biology Professor," 3 October 2005 [2]
- ^ Caltech Media Relations, "Caltech Presidential Inauguration — A Student Affair," 30 April 2007 [3]
- ^ Lois E. Beckett, "MIT Professor Fired for Faking Data; MIT biologist and HMS grad may also have falsified data in work at Harvard" (Harvard Crimson, 31 October 2005) [4]
- ^ Bombardieri, Marcella; Cook, Gareth (October 29, 2005). "More doubts raised on fired MIT professor". Boston Globe.
- ^ Reich, E.S. (24 November 2007). "Scientific misconduct report still under wraps". New Scientist (2361): 16.
External links
- Caltech Biology Division Faculty member page
- Baltimore Laboratory at Caltech site
- Autobiography at Nobelprize.org
- David Baltimore's seminars: "Danger from the Wild: HIV, Can We Conquer It?"
- Initial reports of ribonucleic acid-dependent DNA polymerase activity:
- Baltimore D (June 1970). "RNA-dependent DNA polymerase in virions of RNA tumour viruses". Nature. 226 (5252): 1209–11. Bibcode:1970Natur.226.1209B. doi:10.1038/2261209a0. PMID 4316300.
- Temin HM, Mizutani S (June 1970). "RNA-dependent DNA polymerase in virions of Rous sarcoma virus". Nature. 226 (5252): 1211–3. Bibcode:1970Natur.226.1211T. doi:10.1038/2261211a0. PMID 4316301.
- Department of Health & Human Services, Departmental Appeals Board, Research Integrity Adjudications Panel Thereza Imanishi-Kari, Ph.D. appeal ruling (Docket No. A-95-33, Decision No. 1582, 21 June 1996; Presentation missing footnotes 169–235 & footnote reference nos. 170–235).
- Nobel Prize video interview [5]
- "The Discover Magazine Interview with David Baltimore" upon his retirement from the presidency of Caltech in 2006 * PBS interview with Baltimore on AIDS, hepatitis, vaccines and science politics [6]
- 1938 births
- Living people
- American Nobel laureates
- California Institute of Technology faculty
- Fellows of the American Academy of Arts and Sciences
- Fellows of the American Association for the Advancement of Science
- Foreign Members of the Royal Society
- Jewish American scientists
- Massachusetts Institute of Technology faculty
- Members of the European Molecular Biology Organization
- Members of the French Academy of Sciences
- Members of the Pontifical Academy of Sciences
- Members of the United States National Academy of Sciences
- National Medal of Science laureates
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- People from Forest Hills, Queens
- People from Great Neck, New York
- Presidents of the California Institute of Technology
- Swarthmore College alumni
- Presidents of Rockefeller University
- Biotechnologists