PX-1

PX-1
Legal status
Legal status	CA: Schedule II; DE: NpSG (Industrial and scientific use only); UK: Class B;
Identifiers
	IUPAC name (S)-N-(1-amino-1-oxo-3-phenylpropan-2-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide;
CAS Number	2221100-71-4 ;
PubChem CID	125181260;
ChemSpider	32055575;
UNII	BJ7SBQ2H5I;
Chemical and physical data
Formula	C23H26FN3O2
Molar mass	395.478 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N[C@H](C(N)=O)CC1=CC=CC=C1)C2=CN(CCCCCF)C3=C2C=CC=C3;
	InChI InChI=1S/C23H26FN3O2/c24-13-7-2-8-14-27-16-19(18-11-5-6-12-21(18)27)23(29)26-20(22(25)28)15-17-9-3-1-4-10-17/h1,3-6,9-12,16,20H,2,7-8,13-15H2,(H2,25,28)(H,26,29)/t20-/m0/s1; Key:DDVANTXQCRMRFF-FQEVSTJZSA-N;

PX-1 (also known as 5F-APP-PICA and SRF-30) is an indole-based synthetic cannabinoid that has been sold online as a designer drug.^[1]^[2]

Legality

Sweden's public health agency suggested classifying PX-1 as hazardous substance on November 10, 2014.^[3]

PX-1 is listed in the Fifth Schedule of the Misuse of Drugs Act (MDA) and therefore illegal in Singapore as of May 2015.^[4]

^ "PX 1". Cayman Chemical. Retrieved 15 July 2015.
^ Presley BC, Logan BK, Jansen-Varnum SA (December 2019). "Phase I metabolism of synthetic cannabinoid receptor agonist PX-1 (5F-APP-PICA) via incubation with human liver microsomes and UHPLC-HRMS". Biomedical Chromatography. 34 (3): e4786. doi:10.1002/bmc.4786. PMID 31863591.
^ "Cannabinoider föreslås bli klassade som hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. Retrieved 16 July 2015.
^ "Misuse of Drugs Act". Singapore Government. 30 April 2015. Retrieved 24 July 2015.

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