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Cannabinodiol Legal status
5'-Methyl-4-pentyl-2'-(prop-1-en-2-yl)-[1,1'-biphenyl]-2,6-diol
CAS Number PubChem CID ChemSpider CompTox Dashboard (EPA ) Formula C 21 H 26 O 2 Molar mass 310.437 g·mol−1 3D model (JSmol )
CCCCCC1=CC(=C(C(=C1)O)C2=C(C=CC(=C2)C)C(=C)C)O
InChI=1S/C21H26O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h9-13,22-23H,2,5-8H2,1,3-4H3
Key:TWKHUZXSTKISQC-UHFFFAOYSA-N
Cannabinodiol (also known as Cannabidinodiol , CBDL and CBND )[ 1] is a phytocannabinoid that is present in the plant Cannabis sativa at low concentrations.[ 2] It is the fully aromatized derivative of cannabidiol (CBD) and can occur as a product of the photochemical conversion of cannabinol (CBN).[ 3]
See also
References
^ Sean D. McAllister; Pierre-Yves Desprez (21 July 2015). "Patent US9084771 - Methods and compositions for treating cancer" . Sutter West Bay Hospitals .
^ Robert J.J.Ch, Lousberg; Ludwig Bercht, C. A.; van Ooyen, Ronald; Spronck, Hubertus J. W. (1 January 1977). "Cannabinodiol: Conclusive identification and synthesis of a new cannabinoid from Cannabis sativa " . Phytochemistry . 16 (5): 595–597. doi :10.1016/0031-9422(77)80023-X .
^ ElSohly, Mahmoud A.; Slade, Desmond (22 December 2005). "Chemical constituents of marijuana: The complex mixture of natural cannabinoids" . Life Sciences . NATURECEUTICALS (NATURAL PRODUCTS), NUTRACEUTICALS, HERBAL BOTANICALS, AND PSYCHOACTIVES: DRUG DISCOVERY AND DRUG-DRUG INTERACTIONS Volume I: Natureceuticals (Natural Products), Herbal Botanicals, Psychoactive Hallucinogens and Related Products. 78 (5): 539–548. doi :10.1016/j.lfs.2005.09.011 . PMID 16199061 .
Phytocannabinoids (comparison )
Cannabibutols Cannabichromenes Cannabicyclols Cannabidiols Cannabielsoins Cannabigerols Cannabiphorols Cannabinols Cannabitriols Cannabivarins Delta-8-tetrahydrocannabinols Delta-9-tetrahydrocannabinols Delta-10-Tetrahydrocannabinols Miscellaneous cannabinoids Active metabolites
Endocannabinoids Synthetic cannabinoid receptor agonists / neocannabinoids
Classical cannabinoids (dibenzopyrans) Non-classical cannabinoids Adamantoylindoles Benzimidazoles Benzoylindoles Cyclohexylphenols Eicosanoids Indazole-3- carboxamides Indole-3-carboxamides Indole-3-carboxylates Naphthoylindazoles Naphthoylindoles Naphthoylpyrroles Naphthylmethylindenes Naphthylmethylindoles Phenylacetylindoles Pyrazolecarboxamides Tetramethylcyclo- propanoylindazoles Tetramethylcyclo- propanoylindoles Others
Allosteric CBR Tooltip Cannabinoid receptor ligands Endocannabinoid enhancers (inactivation inhibitors) Anticannabinoids (antagonists/inverse agonists/antibodies)
Receptor (ligands )
CB1 Tooltip Cannabinoid receptor type 1
Agonists(abridged,full list ) Inverse agonists Antagonists
CB2 Tooltip Cannabinoid receptor type 2
Agonists
2-AG
2-AGE (noladin ether)
3,3'-Diindolylmethane
4-O-Methylhonokiol
α-Amyrin · β-Amyrin
A-796,260
A-834,735
A-836,339
AM-1172
AM-1221
AM-1235
AM-1241
AM-2232
Anandamide
AZ-11713908
Cannabinol
Caryophyllene
CB-13
CBS-0550
CP 55,940
GW-405,833 (L-768,242)
GW-842,166X
HU-308
JTE 7-31
JWH-007
JWH-015
JWH-018
JWH-73
JWH-133
L-759,633
L-759,656
Lenabasum (anabasum)
Magnolol
MDA-19
Nabitan
NADA
Olorinab (APD-371)
PF-03550096
S-444,823
SER-601
Serinolamide A
UR-144
Tedalinab
THC (dronabinol)
THCV
Tetrahydromagnolol
Virodhamine
Antagonists
NAGly (GPR18 )
GPR55
GPR119
Transporter (modulators )
eCBTs Tooltip Endocannabinoid transporter
Enzyme (modulators )
Others
Others: 2-PG (directly potentiates activity of 2-AG at CB1 receptor)
ARN-272 (FAAH-like anandamide transporter inhibitor)