SARS-CoV-2 Lambda variant: Difference between revisions
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Lambda variant, also known as '''lineage C.37''', is a [[Variants of SARS-CoV-2|variant]] of [[SARS-CoV-2]], the [[virus]] that causes [[COVID-19]].<ref name=WHOlambda>{{Cite web|title=Tracking SARS-CoV-2 variants|url=https://www.who.int/activities/tracking-SARS-CoV-2-variants|url-status=live|access-date=2021-06-17|website=[[World Health Organization]]|language=en}}</ref> It was first detected in [[Peru]] in December 2020.<ref name=WHOlambda/> On 14 June 2021, the [[World Health Organization|World Health Organization (WHO)]] named it Lambda variant<ref name=WHOlambda/> and designated it as a [[variant of interest]].<ref name="who-variants">{{Cite web |title=Tracking SARS-CoV-2 variants |url=https://www.who.int/en/activities/tracking-SARS-CoV-2-variants/ |url-status=live |website=who.int |language=en |publisher=World Health Organization}} Updated frequently.</ref> It has spread to at least 30 countries<ref name="ultralambdaaustralia">{{cite news|url=https://www.nzherald.co.nz/world/covid-19-coronavirus-ultra-contagious-lambda-variant-detected-in-australia/LAUYIDU2L7SSWMX6IQDTOYCX6A/|title=Covid 19 coronavirus: Ultra-contagious Lambda variant detected in Australia}}</ref> around the world and may be more resistant to vaccine compared to other strains.<ref name="lambdawionews">{{cite news|url=https://www.wionews.com/world/covid-19-lambda-variant-may-be-more-resistant-to-vaccines-than-other-strains-396116|title=COVID-19: Lambda variant may be more resistant to vaccines than other strains}}</ref><ref name="lambdaindependentUK">{{cite news|url=https://www.independent.co.uk/news/health/covid-uk-lambda-variant-peru-b1878416.html|title=Lambda variant: What is the new strain of Covid detected in the UK?}}</ref> It is also suggested that the Lambda variant more infectious than the [[SARS-CoV-2 Alpha variant|Alpha]] or [[Gamma variant]].<ref name="lambdawionews"></ref> |
The '''SARS-CoV-2 Lambda variant''', also known as '''lineage C.37''', is a [[Variants of SARS-CoV-2|variant]] of [[SARS-CoV-2]], the [[virus]] that causes [[COVID-19]].<ref name=WHOlambda>{{Cite web|title=Tracking SARS-CoV-2 variants|url=https://www.who.int/activities/tracking-SARS-CoV-2-variants|url-status=live|access-date=2021-06-17|website=[[World Health Organization]]|language=en}}</ref> It was first detected in [[Peru]] in December 2020.<ref name=WHOlambda/> On 14 June 2021, the [[World Health Organization|World Health Organization (WHO)]] named it Lambda variant<ref name=WHOlambda/> and designated it as a [[variant of interest]].<ref name="who-variants">{{Cite web |title=Tracking SARS-CoV-2 variants |url=https://www.who.int/en/activities/tracking-SARS-CoV-2-variants/ |url-status=live |website=who.int |language=en |publisher=World Health Organization}} Updated frequently.</ref> It has spread to at least 30 countries<ref name="ultralambdaaustralia">{{cite news|url=https://www.nzherald.co.nz/world/covid-19-coronavirus-ultra-contagious-lambda-variant-detected-in-australia/LAUYIDU2L7SSWMX6IQDTOYCX6A/|title=Covid 19 coronavirus: Ultra-contagious Lambda variant detected in Australia}}</ref> around the world and may be more resistant to vaccine compared to other strains.<ref name="lambdawionews">{{cite news|url=https://www.wionews.com/world/covid-19-lambda-variant-may-be-more-resistant-to-vaccines-than-other-strains-396116|title=COVID-19: Lambda variant may be more resistant to vaccines than other strains}}</ref><ref name="lambdaindependentUK">{{cite news|url=https://www.independent.co.uk/news/health/covid-uk-lambda-variant-peru-b1878416.html|title=Lambda variant: What is the new strain of Covid detected in the UK?}}</ref> It is also suggested that the Lambda variant more infectious than the [[SARS-CoV-2 Alpha variant|Alpha]] or [[Gamma variant]].<ref name="lambdawionews"></ref> |
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Revision as of 11:36, 9 July 2021
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The SARS-CoV-2 Lambda variant, also known as lineage C.37, is a variant of SARS-CoV-2, the virus that causes COVID-19.[1] It was first detected in Peru in December 2020.[1] On 14 June 2021, the World Health Organization (WHO) named it Lambda variant[1] and designated it as a variant of interest.[2] It has spread to at least 30 countries[3] around the world and may be more resistant to vaccine compared to other strains.[4][5] It is also suggested that the Lambda variant more infectious than the Alpha or Gamma variant.[4]
Mutations
The Lambda genome has the following amino acid mutations, all of which are in the virus's spike protein code: G75V, T76I, Δ246-252, L452Q, F490S, D614G and T859N.[6]
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![Amino acid mutations of SARS-CoV-2 Lambda variant plotted on a genome map of SARS-CoV-2 with a focus on the spike.[7]](//upload.wikimedia.org/wikipedia/commons/thumb/3/3a/SARS-CoV-2_Lambda_variant.svg/3658px-SARS-CoV-2_Lambda_variant.svg.png)
Amino acid mutations of SARS-CoV-2 Lambda variant plotted on a genome map of SARS-CoV-2 with a focus on the spike.[7]
![Amino acid mutations of SARS-CoV-2 Lambda variant plotted on a genome map of SARS-CoV-2 with a focus on the spike.[7]](/wiki/File:SARS-CoV-2_Lambda_variant.svg)
History
First samples of the Lambda variant were detected in Peru in December 2020 and by April 2021, over eighty percent of new cases of COVID-19 in Peru were from the new variant.[1][8]
By June 2021, the Lambda variant had begun to spread through South America and was detected in twenty-nine countries in total, especially in Argentina, Chile and Ecuador.[8][9] The WHO designated the Lambda variant as a "variant of interest" on 14 June 2021.[1] In mid-June 2021, 90.6% of new COVID-19 cases in Arequipa and 78.1% of new cases in Cusco were the Lambda variant according to the Peruvian Ministry of Health.[10]
On 6 July Australia reported its first case of the Lambda variant in a overseas traveller who had been in a New South Wales quarantine hotel in April.[11]
Statistics
| Cases by country (Updated as of 1 July 2021) GISAID[12] | ||
|---|---|---|
| Country | Confirmed cases | Last reported case |
| Chile | 840 | 13 June 2021 |
| USA | 608 | 22 June 2021 |
| Peru | 239 | 30 May 2021 |
| Germany | 99 | 17 June 2021 |
| Mexico | 89 | 16 June 2021 |
| Argentina | 87 | 12 May 2021 |
| Ecuador | 50 | 20 June 2021 |
| Spain | 50 | 18 June 2021 |
| Israel | 25 | 09 May 2021 |
| Colombia | 19 | 08 May 2021 |
| France | 13 | 10 June 2021 |
| Italy | 10 | 22 June 2021 |
| Saint Kitts and Nevis | 10 | 06 June 2021 |
| Switzerland | 9 | 17 June 2021 |
| Egypt | 8 | 02 May 2021 |
| United Kingdom | 7 | 18 June 2021 |
| Brazil | 4 | 06 June 2021 |
| Canada | 4 | |
| Poland | 3 | 11 June 2021 |
| Aruba | 2 | 02 June 2021 |
| Australia | 1 | 03 April 2021 |
| Curacao | 1 | 17 February 2021 |
| Czech Republic | 1 | 02 June 2021 |
| Denmark | 1 | 12 April 2021 |
| Netherlands | 1 | 24 May 2021 |
| Portugal | 1 | 06 April 2021 |
| Turkey | 1 | 07 May 2021 |
| Uruguay | 1 | 15 April 2021 |
| Zimbabwe | 1 | 28 December 2020 |
| World (29 countries) | Total: 2,184 | Total as of 1 July 2021 |
See also
References
- ^ a b c d e "Tracking SARS-CoV-2 variants". World Health Organization. Retrieved 2021-06-17.
{{cite web}}: CS1 maint: url-status (link) - ^ "Tracking SARS-CoV-2 variants". who.int. World Health Organization.
{{cite web}}: CS1 maint: url-status (link) Updated frequently. - ^ "Covid 19 coronavirus: Ultra-contagious Lambda variant detected in Australia".
- ^ a b "COVID-19: Lambda variant may be more resistant to vaccines than other strains".
- ^ "Lambda variant: What is the new strain of Covid detected in the UK?".
- ^ Robertson, Sally (27 June 2021). "Lambda lineage of SARS-CoV-2 has potential to become variant of concern". news-medical.net. Retrieved 2021-07-05.
The Lambda variant also contained a novel deletion (Δ246-252) and multiple nonsynonymous mutations (G75V, T76I, L452Q, F490S, D614G, and T859N) in the gene that encodes the viral spike protein.
- ^ "Spike Variants: Lambda variant, aka B.1.1.1". covdb.stanford.edu. Stanford University Coronavirus Antiviral & Resistance Database. 1 July 2021. Retrieved 2021-07-05.
- ^ a b "WHO reports on Lambda: the new variant of COVID-19 that is affecting South America". Entrepreneur. 2021-06-17. Retrieved 2021-06-17.
{{cite web}}: CS1 maint: url-status (link) - ^ Mendez, Rich (2021-06-16). "WHO says delta Covid variant has now spread to 80 countries and it keeps mutating". CNBC. Retrieved 2021-06-17.
{{cite web}}: CS1 maint: url-status (link) - ^ Acosta, Sebastián (2021-06-16). "Coronavirus en Perú | Minsa: El 90,6 % de los contagios en Arequipa se deben a la variante Lambda". RPP (in Spanish). Retrieved 17 June 2021.
- ^ (News.com.au)
- ^ "GISAID - hCov19 Variants". www.gisaid.org. Retrieved 2021-07-02.