5F-CUMYL-PINACA

5F-CUMYL-PINACA
Legal status
Legal status	CA: Schedule II; UK: Controlled as psychoactive substance; Illegal in Sweden;
Identifiers
	IUPAC name 1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide;
CAS Number	1400742-16-6;
PubChem CID	86274158;
ChemSpider	35228406;
CompTox Dashboard (EPA)	DTXSID701032564 ;
Chemical and physical data
Formula	C22H26FN3O
Molar mass	367.5 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(NC(C)(C)C1=CC=CC=C1)C2=NN(CCCCCF)C3=C2C=CC=C3;
	InChI InChI=1S/C22H26FN3O/c1-22(2,17-11-5-3-6-12-17)24-21(27)20-18-13-7-8-14-19(18)26(25-20)16-10-4-9-15-23/h3,5-8,11-14H,4,9-10,15-16H2,1-2H3,(H,24,27); Key:XSHGVIPHMOTDCS-UHFFFAOYSA-N;

5F-CUMYL-PINACA (also known as SGT-25 and sometimes sold in e-cigarette form as C-Liquid)^[1] is an indazole-3-carboxamide based synthetic cannabinoid.^[2] 5F-CUMYL-PINACA acts as a potent agonist for the cannabinoid receptors, with approximately 4x selectivity for CB₁, having an EC₅₀ of <0.1 nM for human CB₁ receptors and 0.37nM for human CB₂ receptors.^[3]

Legal status

Sweden's public health agency suggested classifying 5F-CUMYL-PINACA as a hazardous substance on November 10, 2014.^[4]

^ Verena Angerer; Bjoern Moosmann; Florian Franz; Volker Auwärter (2015). "5F-cumyl-PINACA in 'e-liquids' for electronic cigarettes – A new type of synthetic cannabinoid in a trendy product" (PDF). Insitute of Forensic Medicine, Forensic Toxicology, Medical Center – University of Freiburg, Germany.
^ "5F-CUMYL-PINACA". Cayman Chemical. Retrieved 11 July 2015.
^ Bowden; et al. (11 April 2013). "Patent WO 2014167530 - Cannabinoid compounds". New Zealand Patent application 623626. Retrieved 11 July 2015.
^ "Cannabinoider föreslås bli klassade som hälsofarlig vara" (in Swedish). Public Health Agency of Sweden. 10 November 2014. Retrieved 11 July 2015. {{cite web}}: Unknown parameter |trans_title= ignored (|trans-title= suggested) (help)

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