40S ribosomal protein S18

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Available structures
PDB Ortholog search: PDBe RCSB
Aliases RPS18, D6S218E, HKE3, KE-3, KE3, S18, ribosomal protein S18
External IDs MGI: 98146 HomoloGene: 88764 GeneCards: RPS18
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) n/a Chr 17: 33.95 – 33.96 Mb
PubMed search [1] [2]
View/Edit Human View/Edit Mouse

40S ribosomal protein S18 is a protein that in humans is encoded by the RPS18 gene.[3][4][5]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S13P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S13) is involved in the binding of fMet-tRNA, and thus, in the initiation of translation. This gene is an ortholog of mouse Ke3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[5]


  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Chassin D, Bellet D, Koman A (Mar 1993). "The human homolog of ribosomal protein S18". Nucleic Acids Res. 21 (3): 745. PMC 309181Freely accessible. PMID 8441687. doi:10.1093/nar/21.3.745. 
  4. ^ Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. PMID 9582194. doi:10.1101/gr.8.5.509. 
  5. ^ a b "Entrez Gene: RPS18 ribosomal protein S18". 

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