ICI-190,622: Difference between revisions
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| IUPAC_name = 4-amino-1-pent-3-ynyl-N-prop-2-enylpyrazolo[3,4-b]pyridine-5-carboxamide |
| IUPAC_name = 4-amino-1-pent-3-ynyl-N-prop-2-enylpyrazolo[3,4-b]pyridine-5-carboxamide |
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Revision as of 15:25, 1 March 2011
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| Formula | C15H17N5O |
| Molar mass | 283.328 g/mol g·mol−1 |
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ICI-190,622 is an anxiolytic drug used in scientific research. It is a pyrazolopyridine derivative, related to other anxiolytic compounds such as tracazolate, and more distantly to zaleplon. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.[1][2]
See also
References
- ^ Patel JB, Meiners BA, Salama AI, Malick JB, U'Prichard DC, Giles RE, Goldberg ME, Bare TM (1988). "Preclinical studies with pyrazolopyridine non-benzodiazepine anxiolytics: ICI 190,622". Pharmacology, Biochemistry, and Behavior. 29 (4): 775–9. doi:10.1016/0091-3057(88)90205-5. PMID 2901116.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ Bare TM, McLaren CD, Campbell JB, Firor JW, Resch JF, Walters CP, Salama AI, Meiners BA, Patel JB (1989). "Synthesis and structure-activity relationships of a series of anxioselective pyrazolopyridine ester and amide anxiolytic agents". Journal of Medicinal Chemistry. 32 (12): 2561–73. doi:10.1021/jm00132a011. PMID 2573731.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link)
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