3,3-Diethyl-2-pyrrolidinone

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Caftaric (talk | contribs) at 08:02, 4 September 2017 (in Caenorhabditis elegans). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

3,3-Diethyl-2-pyrrolidinone
Clinical data
ATC code
  • none
Identifiers
  • 3,3-diethyl-2-pyrrolidinone
CAS Number
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.162.031 Edit this at Wikidata
Chemical and physical data
FormulaC8H15NO
Molar mass141.210 g/mol g·mol−1
3D model (JSmol)
  • CCC1(CC)CCNC1=O
  • InChI=1S/C8H15NO/c1-3-8(4-2)5-6-9-7(8)10/h3-6H2,1-2H3,(H,9,10) checkY
  • Key:WYPUMACPRYGQOM-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

3,3-Diethyl-2-pyrrolidinone (DEABL) is an anticonvulsant drug most closely related to pyrithyldione and gabapentin.[1] It was found to extend lifespan in the nematode worms Caenorhabditis elegans.[2]

References

  1. ^ Hill, MW; Reddy, PA; Covey, DF; Rothman, SM (1998). "Contribution of subsaturating GABA concentrations to IPSCs in cultured hippocampal neurons". Journal of Neuroscience. 18 (14): 5103–11. PMID 9651194.
  2. ^ Evason, K; Huang, C; Yamben, I; Covey, DF; Kornfeld, K (2005). "Anticonvulsant medications extend worm life-span". Science. 307 (5707): 258–62. doi:10.1126/science.1105299. PMID 15653505.


Stub icon

This anticonvulsant-related article is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=3,3-Diethyl-2-pyrrolidinone&oldid=798866735"