MRPL17

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MRPL17
Protein MRPL17 PDB 2cqm.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MRPL17, L17mt, LIP2, MRP-L17, MRP-L26, RPL17L, RPML26, mitochondrial ribosomal protein L17
External IDs MGI: 1351608 HomoloGene: 32526 GeneCards: MRPL17
RNA expression pattern
PBB GE MRPL17 222216 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_022061

NM_025301

RefSeq (protein)

NP_071344

NP_079577.1
NP_079577

Location (UCSC) Chr 11: 6.68 – 6.68 Mb Chr 7: 105.8 – 105.81 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

39S ribosomal protein L17, mitochondrial is a protein that in humans is encoded by the MRPL17 gene.[3]

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.[3]

References[edit]

Further reading[edit]