60S ribosomal protein L34

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RPL34
Available structures
PDB Human UniProt search: PDBe RCSB
Identifiers
Aliases RPL34, L34, ribosomal protein L34
External IDs MGI: 3648994 HomoloGene: 137646 GeneCards: RPL34
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

XM_006517804

RefSeq (protein)

n/a

Location (UCSC) Chr 4: 108.62 – 108.63 Mb n/a
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

60S ribosomal protein L34 is a protein that in humans is encoded by the RPL34 gene.[3][4][5]

Function[edit]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L34E family of ribosomal proteins. It is located in the cytoplasm. This gene originally was thought to be located at 17q21, but it has been mapped to 4q. Transcript variants derived from alternative splicing, alternative transcription initiation sites, and/or alternative polyadenylation exist; these variants encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (May 1998). "A map of 75 human ribosomal protein genes". Genome Research. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194. 
  4. ^ Rommens JM, Durocher F, McArthur J, Tonin P, LeBlanc JF, Allen T, Samson C, Ferri L, Narod S, Morgan K (August 1995). "Generation of a transcription map at the HSD17B locus centromeric to BRCA1 at 17q21". Genomics. 28 (3): 530–42. doi:10.1006/geno.1995.1185. PMID 7490091. 
  5. ^ a b "Entrez Gene: RPL34 ribosomal protein L34". 

Further reading[edit]