Amfonelic acid: Difference between revisions
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| IUPAC_name = 1-ethyl-4-oxo-7-(phenylmethyl)-1,8-naphthyridine-3-carboxylic acid |
| IUPAC_name = 1-ethyl-4-oxo-7-(phenylmethyl)-1,8-naphthyridine-3-carboxylic acid |
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| image = Amfonelic_acid_.png |
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| ChemSpiderID = 2052 |
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Revision as of 19:16, 9 March 2011
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Formula | C18H16N2O3 |
Molar mass | 308.331 g/mol g·mol−1 |
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Amfonelic acid (AFA; WIN 25,978) is a psychoactive drug and research chemical used in scientific studies. It acts as a potent and highly selective dopamine reuptake inhibitor (DRI).[1][2] It has a moderately long half-life of approximately 12 hours.
See also
References
- ^ Fuller RW, Perry KW, Bymaster FP, Wong DT. (1978). "Comparative effects of pemoline, amfonelic acid and amphetamine on dopamine uptake and release in vitro and on brain 3,4-dihydroxyphenylacetic acid concentration in spiperone-treated rats". J Pharm Pharmacol. 30 (3): 197–198. PMID 24701.
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: CS1 maint: multiple names: authors list (link) - ^ McMillen BA, Shore PA. (1978). "Amfonelic acid, a non-amphetamine stimulant, has marked effects on brain dopamine metabolism but not noradrenaline metabolism: association with differences in neuronal storage systems". J Pharm Pharmacol. 30 (7): 464–466. PMID 27622.