4-HO-MiPT

4-HO-MiPT
Clinical data
Routes of; administration	Oral, IV, intranasal, rectal
ATC code	None;
Legal status
Legal status	UK: notscheduled; US: notscheduled; See Legality;
Pharmacokinetic data
Metabolism	Liver
Elimination half-life	4-6 Hours
Excretion	Kidneys/Urine
Identifiers
	IUPAC name 3-(2-[Isopropyl(methyl)amino]ethyl)-1H-indol-4-ol;
CAS Number	77872-43-6 ;
PubChem CID	10082683;
ChemSpider	8258221 ;
ChEMBL	ChEMBL171419 ;
CompTox Dashboard (EPA)	DTXSID30228492 ;
Chemical and physical data
Formula	C14H20N2O
Molar mass	232.32 g/mol g·mol−1
3D model (JSmol)	Interactive image;
Melting point	123 to 125 °C (253 to 257 °F)
	SMILES CN(C(C)C)CCC2=CNC1=CC=CC(O)=C12;
	InChI InChI=1S/C14H20N2O/c1-10(2)16(3)8-7-11-9-15-12-5-4-6-13(17)14(11)12/h4-6,9-10,15,17H,7-8H2,1-3H3 ; Key:RXKGHZCQFXXWFQ-UHFFFAOYSA-N ;
	(what is this?) (verify)

Miprocin (4-hydroxy-N-methyl-N-isopropyl tryptamine, 4-Hydroxy-MiPT) is a artificially-made, substituted aromatic compound and a lesser-known psychedelic drug from the tryptamine family. Miprocin is part of the class of drugs known as serotonergic psychedelics (which includes magic mushrooms, LSD and mescaline), and its effects and molecular structure resemble that of the tryptamine psilocin. To date, there have been no reports of deaths from 4-HO-MiPT.

History

4-HO-MiPT was first synthesized by Alexander Shulgin. In his book TIHKAL (Tryptamines I Have Known and Loved). 4-HO-MiPT is a synthetic psychedelic considered similar in activity to psilocin. It is relatively uncommon and has only a short history of human use.

Chemistry

Miprocin is the 4-hydroxyl analog of the chemical N-Methyl-N-isopropyltryptamine as well as the two-carbon homologue and possible structural analog of 4-HO-DMT.

Pharmacology

Miprocin is a serotonergic. Its method of action comes from its partial agonist activity at 5-HT_2A and 5-HT_1A serotonin receptors and serotonin neurotransmitters located in the prefrontal cortex in the human brain.

Toxicity

Very little is known about the overrall toxicity of Miprocin. The chemicial structure of it is very similar to Psilocin and it isn't known to be associated with compulsive use and physical dependence however, this being a research chemical and because its use is so uncommon, it should therefore be considered & treated like an experimental chemical. Although some people are willing to ingest these chemicals for their effects, it is not reasonable to assume that this chemical is in any way 'safe' to use recreationally.

Dosage

Miprocin Vial

100 milligram phial of 4-HO-MiPT.

Miprocin (Fumarate)	Oral Dose
Threshold	5 mg-10 mg
Light	9 mg-14 mg
Common	12 mg-20 mg
Strong	18 mg-30 mg
Heavy	25 mg+
Onset	After Effects
15 - 45 minutes (depending on stomach contents)	1 - 4 hours

Effects

Erowid & BlueLight.ru reports the following effects:^[1]^[2]

Positive

Psilocybin-like Open & Closed-eye visuals
Creative or abstract thinking
Increased giggling and laughing
Out of body experience, light disassociation (if desired)
Mood lift, euphoria
Intensification of tactile sensations, smell, etc
Increased appetite
Heighten sexual interest
Diminished aggression, hostility, and jealousy
Diminished fear, anxiety, and insecurity
Substantial enhancement of the appreciation for quality of music

Neutral

Mydriasis
Colour alteration
Time perception alteration
Synesthesia
Sedation / Somnolence
Feelings of body twitching
General change in consciousness
Auditory distortions, pitch shifts
Visual distortions, open and closed-eye patterning, movement trails, shifting colors

Side effects

Body tremors and / or convulsion
Mild vertigo
Slight headache and nausea
Possible confusion
Light-headedness
Possible xerostomia
May exacerbate latent or existing mental disorders
Possible minor jaw-clenching
Slight change in body temperature

Duration

The duration is listed as 4-6 hours, although other sources list the duration as 5-8 hours, depending on certain variables (such as metabolism, food interaction).

Legality

4-HO-MiPT is a unscheduled drug in the United States. It may be considered an analog of psilocin, in which case could lead to persecution under the Analog Act of the USA.

The substance could also be considered illegal in the UK under the Misuse of Drugs Act 1971.

Miprocin was scheduled as "hälsofarliga varor" (health-threatening substances, having no acceptable medical use) in Sweden on Nov 1, 2005.^[3]

References

External links

Template:TiHKAL

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[1] Erowid Experience Vaults: 4-Hydroxy-MiPT

[2] The Big & Dandy 4-HO-MiPT Thread.

[3] Svensk författningssamling (SFS)

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