KIF2C

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Kinesin family member 2C
Protein KIF2C PDB 1v8j.png
PDB rendering based on 1v8j.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols KIF2C ; KNSL6; MCAK
External IDs OMIM604538 MGI1921054 HomoloGene21355 ChEMBL: 5967 GeneCards: KIF2C Gene
RNA expression pattern
PBB GE KIF2C 211519 s at tn.png
PBB GE KIF2C 209408 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 11004 73804
Ensembl ENSG00000142945 ENSMUSG00000028678
UniProt Q99661 Q922S8
RefSeq (mRNA) NM_006845 NM_134471
RefSeq (protein) NP_006836 NP_608301
Location (UCSC) Chr 1:
45.21 – 45.23 Mb
Chr 4:
117.16 – 117.18 Mb
PubMed search [1] [2]

Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene.[1][2]

The protein encoded by this gene is a member of kinesin-like protein family. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation.[2]

References[edit]

  1. ^ Kim IG, Jun DY, Sohn U, Kim YH (Feb 1998). "Cloning and expression of human mitotic centromere-associated kinesin gene". Biochim Biophys Acta 1359 (3): 181–6. PMID 9434124. 
  2. ^ a b "Entrez Gene: KIF2C kinesin family member 2C". 

Further reading[edit]