MYO1F

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Myosin IF
Identifiers
Symbol MYO1F
External IDs OMIM601480 MGI107711 HomoloGene56276 GeneCards: MYO1F Gene
RNA expression pattern
PBB GE MYO1F 213733 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 4542 17916
Ensembl ENSG00000142347 ENSMUSG00000024300
UniProt O00160 n/a
RefSeq (mRNA) NM_012335 NM_053214
RefSeq (protein) NP_036467 NP_444444
Location (UCSC) Chr 19:
8.59 – 8.64 Mb
Chr 17:
33.56 – 33.61 Mb
PubMed search [1] [2]

Myosin-If is a protein that in humans is encoded by the MYO1F gene.[1][2][3]

It is expressed mainly in the immune system and might be involved in cell adhesion and motility.[4] It is a candidate gene for (among other things) nonsyndromic deafness.[5]

References[edit]

  1. ^ Crozet F, el Amraoui A, Blanchard S, Lenoir M, Ripoll C, Vago P, Hamel C, Fizames C, Levi-Acobas F, Depetris D, Mattei MG, Weil D, Pujol R, Petit C (Apr 1997). "Cloning of the genes encoding two murine and human cochlear unconventional type I myosins". Genomics 40 (2): 332–41. doi:10.1006/geno.1996.4526. PMID 9119401. 
  2. ^ Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, Anderson BL, Sherr EH, Chen ZY, Greene LA, Ward DC, Corey DP, Mooseker MS, Copeland NG, Jenkins NA (Feb 1997). "Mapping of unconventional myosins in mouse and human". Genomics 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266. 
  3. ^ "Entrez Gene: MYO1F myosin IF". 
  4. ^ Kim SV, Mehal WZ, Dong X, Heinrich V, Pypaert M, Mellman I, Dembo M, Mooseker MS, Wu D, Flavell RA (October 2006). "Modulation of cell adhesion and motility in the immune system by Myo1f". Science 314 (5796): 136–9. doi:10.1126/science.1131920. PMID 17023661. 
  5. ^ Chen AH, Stephan DA, Hasson T, Fukushima K, Nelissen CM, Chen AF, Jun AI, Ramesh A, Van Camp G, Smith RJ (August 2001). "MYO1F as a candidate gene for nonsyndromic deafness, DFNB15". Arch. Otolaryngol. Head Neck Surg. 127 (8): 921–5. doi:10.1001/archotol.127.8.921. PMID 11493199. 

Further reading[edit]