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Myosin, heavy chain 14, non-muscle
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols MYH14 ; DFNA4; DFNA4A; MHC16; MYH17; NMHC II-C; NMHC-II-C; PNMHH; myosin
External IDs OMIM608568 MGI1919210 HomoloGene23480 GeneCards: MYH14 Gene
EC number
RNA expression pattern
PBB GE MYH14 217545 at tn.png
PBB GE MYH14 217660 at tn.png
PBB GE MYH14 219946 x at tn.png
More reference expression data
Species Human Mouse
Entrez 79784 71960
Ensembl ENSG00000105357 ENSMUSG00000030739
UniProt Q7Z406 Q6URW6
RefSeq (mRNA) NM_001077186 NM_001271538
RefSeq (protein) NP_001070654 NP_001258467
Location (UCSC) Chr 19:
50.69 – 50.81 Mb
Chr 7:
44.61 – 44.67 Mb
PubMed search [1] [2]

Myosin-14 is a protein that in humans is encoded by the MYH14 gene.[1][2][3]

This gene encodes a member of the myosin superfamily. Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene.[3]


  1. ^ Leal A, Endele S, Stengel C, Huehne K, Loetterle J, Barrantes R, Winterpacht A, Rautenstrauss B (Aug 2003). "A novel myosin heavy chain gene in human chromosome 19q13.3". Gene 312: 165–71. doi:10.1016/S0378-1119(03)00613-9. PMID 12909352. 
  2. ^ Donaudy F, Snoeckx R, Pfister M, Zenner HP, Blin N, Di Stazio M, Ferrara A, Lanzara C, Ficarella R, Declau F, Pusch CM, Nurnberg P, Melchionda S, Zelante L, Ballana E, Estivill X, Van Camp G, Gasparini P, Savoia A (Mar 2004). "Nonmuscle Myosin Heavy-Chain Gene MYH14 Is Expressed in Cochlea and Mutated in Patients Affected by Autosomal Dominant Hearing Impairment (DFNA4)". Am J Hum Genet 74 (4): 770–6. doi:10.1086/383285. PMC 1181955. PMID 15015131. 
  3. ^ a b "Entrez Gene: MYH14 myosin, heavy chain 14". 

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