Troponin T
From Wikipedia, the free encyclopedia
Troponin T is a part of the troponin complex. It binds to tropomyosin, interlocking them to form a troponin-tropomyosin complex.
The tissue specific subtypes are:
- Slow skeletal troponin T1, TNNT1 (19q13.4, 191041)
- Cardiac troponin T2, TNNT2 (1q32, 191045)
- Fast skeletal troponin T3, TNNT3 (11p15.5, 600692)
Troponin T binds to tropomyosin and helps position it on actin [1]. And in a less complicated light, Troponin T modulates contraction of striated muscle [2]
Troponin T was discovered by the German physician Hugo A. Katus at the University of Heidelberg. He developed the troponin T assay.[3]
[edit] References
- ^ marieb, elaine (2004)
- ^ black, joyce (2005)
- ^ "Development of the Cardiac Troponin T Immunoassay". American Association for Clinical Chemistry, Inc. 2008. http://www.clinchem.org/cgi/content/full/54/9/1576. Retrieved 2010-05-01.
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