Portal:Medicine

The Medicine Portal

The color fresco Care of The Sick by Domenico di Bartolo, 1441–1442, depicting the Santa Maria della Scala hospital in Siena, Italy

Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others.

Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of creativity and skill), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ancient philosopher and physician would apply bloodletting according to the theories of humorism. In recent centuries, since the advent of modern science, most medicine has become a combination of art and science (both basic and applied, under the umbrella of medical science). For example, while stitching technique for sutures is an art learned through practice, knowledge of what happens at the cellular and molecular level in the tissues being stitched arises through science.

Prescientific forms of medicine, now known as traditional medicine or folk medicine, remain commonly used in the absence of scientific medicine and are thus called alternative medicine. Alternative treatments outside of scientific medicine with ethical, safety and efficacy concerns are termed quackery. (Full article...)

Featured articles -

Featured articles are displayed here, which represent some of the best content on English Wikipedia.

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  Sorrowing Old Man (At Eternity's Gate), an 1890 portrait by Vincent van Gogh

  
  Major depressive disorder (MDD), also known as clinical depression, is a mental disorder characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, the term was adopted by the American Psychiatric Association for this symptom cluster under mood disorders in the 1980 version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III), and has become widely used since. The disorder causes the second-most years lived with disability, after lower back pain.
  
  The diagnosis of major depressive disorder is based on the person's reported experiences, behavior reported by relatives or friends, and a mental status examination. There is no laboratory test for the disorder, but testing may be done to rule out physical conditions that can cause similar symptoms. The most common time of onset is in a person's 20s, with females affected about twice as often as males. The course of the disorder varies widely, from one episode lasting months to a lifelong disorder with recurrent major depressive episodes. (Full article...)
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  High-resolution computed tomography images of the lower chest in a 16-year-old boy with diffuse panbronchiolitis

  
  Diffuse panbronchiolitis (DPB) is an inflammatory lung disease of unknown cause. It is a severe, progressive form of bronchiolitis, an inflammatory condition of the bronchioles (small air passages in the lungs). The term diffuse signifies that lesions appear throughout both lungs, while panbronchiolitis refers to inflammation found in all layers of the respiratory bronchioles (those involved in gas exchange). DPB causes severe inflammation and nodule-like lesions of terminal bronchioles, chronic sinusitis, and intense coughing with large amounts of sputum production.
  
  The disease is believed to occur when there is susceptibility, or a lack of immune system resistance, to DPB-causing bacteria or viruses, caused by several genes that are found predominantly in individuals of East Asian descent. The highest incidence occurs among Japanese people, followed by Koreans. DPB occurs more often in males and usually begins around age 40. It was recognized as a distinct new disease in the early 1960s and was formally named diffuse panbronchiolitis in 1969. (Full article...)
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  Cartoon in Punch, November 1858

  
  In 1858 a batch of sweets in Bradford, England, was accidentally adulterated with poisonous arsenic trioxide. About five pounds (two kilograms) of sweets were sold to the public, leading to around 20 deaths and over 200 people suffering the effects of arsenic poisoning.
  
  The adulteration of food had been practised in Britain since before the Middle Ages, but from 1800, with increasing urbanisation and the rise in shop-purchased food, adulterants became a growing problem. With the cost of sugar high, replacing it with substitutes was common. For the sweets produced in Bradford, the confectioner was supposed to purchase powdered gypsum, but a mistake at the wholesale chemist meant arsenic was purchased instead. (Full article...)
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  Urine from a person with rhabdomyolysis showing the characteristic brown discoloration as a result of myoglobinuria

  
  Rhabdomyolysis (shortened as rhabdo) is a condition in which damaged skeletal muscle breaks down rapidly, often due to high intensity exercise over a short period. Symptoms may include muscle pains, weakness, vomiting, and confusion. There may be tea-colored urine or an irregular heartbeat. Some of the muscle breakdown products, such as the protein myoglobin, are harmful to the kidneys and can cause acute kidney injury.
  
  
  The muscle damage is most usually caused by a crush injury, strenuous exercise, medications, or a substance use disorder. Other causes include infections, electrical injury, heat stroke, prolonged immobilization, lack of blood flow to a limb, or snake bites as well as intense or prolonged exercise, particularly in hot conditions. Statins (prescription drugs to lower cholesterol) are considered a small risk. Some people have inherited muscle conditions that increase the risk of rhabdomyolysis. The diagnosis is supported by a urine test strip which is positive for "blood" but the urine contains no red blood cells when examined with a microscope. Blood tests show a creatine kinase activity greater than 1000 U/L, with severe disease being above 5000–15000 U/L. (Full article...)
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  Influenza virus

  
  Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms begin one to four (typically two) days after exposure to the virus and last for about two to eight days. Diarrhea and vomiting can occur, particularly in children. Influenza may progress to pneumonia from the virus or a subsequent bacterial infection. Other complications include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems such as asthma and cardiovascular disease.
  
  There are four types of influenza virus: types A, B, C, and D. Aquatic birds are the primary source of influenza A virus (IAV), which is also widespread in various mammals, including humans and pigs. Influenza B virus (IBV) and influenza C virus (ICV) primarily infect humans, and influenza D virus (IDV) is found in cattle and pigs. Influenza A virus and influenza B virus circulate in humans and cause seasonal epidemics, and influenza C virus causes a mild infection, primarily in children. Influenza D virus can infect humans but is not known to cause illness. In humans, influenza viruses are primarily transmitted through respiratory droplets from coughing and sneezing. Transmission through aerosols and surfaces contaminated by the virus also occur. (Full article...)
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  Liver histology is altered in HRS while kidney histology is normal. The upper image is a trichrome stain (chicken wire appearance) cirrhosis of the liver, the most common cause of HRS. The lower image is a PAS stain of normal kidney histology.

  
  Hepatorenal syndrome (HRS) is a life-threatening medical condition that consists of rapid deterioration in kidney function in individuals with cirrhosis or fulminant liver failure. HRS is usually fatal unless a liver transplant is performed, although various treatments, such as dialysis, can prevent advancement of the condition.
  
  HRS can affect individuals with cirrhosis, severe alcoholic hepatitis, or liver failure, and usually occurs when liver function deteriorates rapidly because of a sudden insult such as an infection, bleeding in the gastrointestinal tract, or overuse of diuretic medications. HRS is a relatively common complication of cirrhosis, occurring in 18% of people within one year of their diagnosis, and in 39% within five years of their diagnosis. Deteriorating liver function is believed to cause changes in the circulation that supplies the intestines, altering blood flow and blood vessel tone in the kidneys. The kidney failure of HRS is a consequence of these changes in blood flow, rather than direct damage to the kidney. The diagnosis of hepatorenal syndrome is based on laboratory tests of individuals susceptible to the condition. Two forms of hepatorenal syndrome have been defined: Type 1 HRS entails a rapidly progressive decline in kidney function, while type 2 HRS is associated with ascites (fluid accumulation in the abdomen) that does not improve with standard diuretic medications. (Full article...)
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  Golding Bird, 1840

  
  Golding Bird (9 December 1814 – 27 October 1854) was a British medical doctor and a Fellow of the Royal College of Physicians. He became a great authority on kidney diseases and published a comprehensive paper on urinary deposits in 1844. He was also notable for his work in related sciences, especially the medical uses of electricity and electrochemistry. From 1836, he lectured at Guy's Hospital, a well-known teaching hospital in London and now part of King's College London, and published a popular textbook on science for medical students called Elements of Natural Philosophy.
  
  Having developed an interest in chemistry while still a child, largely through self-study, Bird was far enough advanced to deliver lectures to his fellow pupils at school. He later applied this knowledge to medicine and did much research on the chemistry of urine and of kidney stones. In 1842, he was the first to describe oxaluria, a condition which leads to the formation of a particular kind of stone. (Full article...)
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  Genetics is the study of genes, genetic variation, and heredity in organisms. It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene.
  
  Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the context of a population. Genetics has given rise to a number of subfields, including molecular genetics, epigenetics, and population genetics. Organisms studied within the broad field span the domains of life (archaea, bacteria, and eukarya). (Full article...)
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  Menstrual cycle

  
  The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that makes pregnancy possible. The ovarian cycle controls the production and release of eggs and the cyclic release of estrogen and progesterone. The uterine cycle governs the preparation and maintenance of the lining of the uterus (womb) to receive an embryo. These cycles are concurrent and coordinated, normally last between 21 and 35 days, with a median length of 28 days. Menarche (the onset of the first period) usually occurs around the age of 12 years; menstrual cycles continue for about 30–45 years.
  
  Naturally occurring hormones drive the cycles; the cyclical rise and fall of the follicle stimulating hormone prompts the production and growth of oocytes (immature egg cells). The hormone estrogen stimulates the uterus lining (endometrium) to thicken to accommodate an embryo should fertilization occur. The blood supply of the thickened lining provides nutrients to a successfully implanted embryo. If implantation does not occur, the lining breaks down and blood is released. Triggered by falling progesterone levels, menstruation (a "period", in common parlance) is the cyclical shedding of the lining, and is a sign that pregnancy has not occurred. (Full article...)
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  SARS-CoV-2, a member of the subfamily Coronavirinae

  
  A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898, more than 11,000 of the millions of virus species have been described in detail. The study of viruses is known as virology, a subspeciality of microbiology.
  
  When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent viral particles, or virions, consisting of (i) genetic material, i.e., long molecules of DNA or RNA that encode the structure of the proteins by which the virus acts; (ii) a protein coat, the capsid, which surrounds and protects the genetic material; and in some cases (iii) an outside envelope of lipids. The shapes of these virus particles range from simple helical and icosahedral forms to more complex structures. Most virus species have virions too small to be seen with an optical microscope and are one-hundredth the size of most bacteria. (Full article...)
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  Biopsy of small bowel showing coeliac disease manifested by blunting of villi, crypt hyperplasia, and lymphocyte infiltration of crypts

  
  Coeliac disease (British English) or celiac disease (American English) is a long-term autoimmune disorder, primarily affecting the small intestine, where individuals develop intolerance to gluten, present in foods such as wheat, rye and barley. Classic symptoms include gastrointestinal problems such as chronic diarrhoea, abdominal distention, malabsorption, loss of appetite, and among children failure to grow normally. Non-classic symptoms are more common, especially in people older than two years. There may be mild or absent gastrointestinal symptoms, a wide number of symptoms involving any part of the body, or no obvious symptoms. Coeliac disease was first described in childhood; however, it may develop at any age. It is associated with other autoimmune diseases, such as Type 1 diabetes mellitus and Hashimoto's thyroiditis, among others.
  
  Coeliac disease is caused by a reaction to gluten, a group of various proteins found in wheat and in other grains such as barley and rye. Moderate quantities of oats, free of contamination with other gluten-containing grains, are usually tolerated. The occurrence of problems may depend on the variety of oat. It occurs more often in people who are genetically predisposed. Upon exposure to gluten, an abnormal immune response may lead to the production of several different autoantibodies that can affect a number of different organs. In the small bowel, this causes an inflammatory reaction and may produce shortening of the villi lining the small intestine (villous atrophy). This affects the absorption of nutrients, frequently leading to anaemia. (Full article...)
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  Debora Green (née Jones; born February 28, 1951) is an American physician who pleaded no contest to setting a 1995 fire that burned down her family's home and killed two of her children, and to poisoning her husband with ricin with the intention of causing his death. The case was sensational, and covered heavily by news media, especially in the Kansas–Missouri area, where the crimes occurred. Though Green has petitioned for a new trial twice in recent years, her requests have not been successful.
  
  Green married Michael Farrar in 1979 while practicing as an emergency physician. The marriage was tumultuous, and Farrar filed for divorce in July 1995. Between August and September 1995, Farrar repeatedly fell violently ill, and despite numerous hospitalizations his doctors could not pinpoint the source of his illness. Green's emotional stability deteriorated and she began to drink heavily, even while supervising her children. On October 24, 1995, the Farrar family home, occupied by Green and the couple's three children — Timothy (age 13), Kate (age 10), and Kelly (age 6) — caught fire. Debora Green and Kate escaped without harm. Despite the efforts of firefighters, Timothy and Kelly died in the blaze. Investigation showed that trails of accelerant in the house led back to Green's bedroom, and that the source of Michael Farrar's intractable illness had been ricin, a poison served to him in his food by Green. (Full article...)
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  Portrait by Julian Smith, 1930s

  
  Howard Walter Florey, Baron Florey, OM FRS FRCP (/ˈflɔːri/; 24 September 1898 – 21 February 1968) was an Australian pharmacologist and pathologist who shared the Nobel Prize in Physiology or Medicine in 1945 with Ernst Chain and Sir Alexander Fleming for his role in the development of penicillin.
  
  Although Fleming received most of the credit for the discovery of penicillin, it was Florey and his team at the University of Oxford who made it into a useful and effective drug, ten years after Fleming had abandoned its development. They developed techniques for growing, purifying and manufacturing the drug, tested it for toxicity and efficacy on animals, and carried out the first clinical trials. In 1941, they used it to treat a police constable from Oxford. He started to recover, but subsequently died because Florey was unable, at that time, to make enough penicillin. Later trials in Britain, the United States and North Africa were highly successful. (Full article...)
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  Holmes, c. 1880s

  
  Oliver Wendell Holmes Sr. (/hoʊmz/; August 29, 1809 – October 7, 1894) was an American physician, poet, and polymath based in Boston. Grouped among the fireside poets, he was acclaimed by his peers as one of the best writers of the day. His most famous prose works are the "Breakfast-Table" series, which began with The Autocrat of the Breakfast-Table (1858). He was also an important medical reformer. In addition to his work as an author and poet, Holmes also served as a physician, professor, lecturer, inventor, and, although he never practiced it, he received formal training in law.
  
  Born in Cambridge, Massachusetts, Holmes was educated at Phillips Academy and Harvard College. After graduating from Harvard in 1829, he briefly studied law before turning to the medical profession. He began writing poetry at an early age; one of his most famous works, "Old Ironsides", was published in 1830 and was influential in the eventual preservation of the USS Constitution. Following training at the prestigious medical schools of Paris, Holmes was granted his Doctor of Medicine degree from Harvard Medical School in 1836. He taught at Dartmouth Medical School before returning to teach at Harvard and, for a time, served as dean there. During his long professorship, he became an advocate for various medical reforms and notably posited the controversial idea that doctors were capable of carrying puerperal fever from patient to patient. Holmes retired from Harvard in 1882 and continued writing poetry, novels and essays until his death in 1894. (Full article...)
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  Thyrotoxic periodic paralysis occurs when the thyroid gland releases excessive amounts of thyroxine (thyroid hormone).

  
  Thyrotoxic periodic paralysis (TPP) is a rare condition featuring attacks of muscle weakness in the presence of hyperthyroidism (overactivity of the thyroid gland). Hypokalemia (a decreased potassium level in the blood) is usually present during attacks. The condition may be life-threatening if weakness of the breathing muscles leads to respiratory failure, or if the low potassium levels lead to abnormal heart rhythms. If untreated, it is typically recurrent in nature.
  
  The condition has been linked with genetic mutations in genes that code for certain ion channels that transport electrolytes (sodium and potassium) across cell membranes. The main ones are the L-type calcium channel α1-subunit and potassium inward rectifier 2.6; it is therefore classified as a channelopathy. The abnormality in the channel is thought to lead to shifts of potassium into cells, under conditions of high thyroxine (thyroid hormone) levels, usually with an additional precipitant. (Full article...)

Selected image –

Horizontal optokinetic reflex, a form of physiologic nystagmus.

Photo credit: Student BSMU, GFDL

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  Captain Novolin is a 1992 educational platform video game, developed by Sculptured Software and published by Raya Systems for the Super Nintendo Entertainment System. Starring the eponymous superhero with type 1 diabetes, the game sees the player control Captain Novolin on a quest to save the mayor of Pineville from the supervillain Blubberman. It is a part of educational video game series from Raya that also includes Rex Ronan: Experimental Surgeon, Packy and Marlon, and Bronkie the Bronchiasaurus.
  
  Funding for the game came from Novo Nordisk (makers of the Novolin brand of insulin) and the National Institutes of Health. To promote the game, Novo Nordisk distributed 10,000 free copies to hospitals. During its initial release, the game was positively received by diabetes specialists, as well as children with the condition; but the retrospective reception from video game critics has been poor, and it has been named as one of the worst video games of all time. (Full article...)
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  Ann Bishop (19 December 1899 – 7 May 1990) was a British biologist from Girton College at the University of Cambridge and a Fellow of the Royal Society, one of the few female Fellows of the Royal Society. She was born in Manchester but stayed at Cambridge for the vast majority of her professional life. Her specialties were protozoology and parasitology; early work with ciliate parasites, including the one responsible for blackhead disease in the domesticated turkey, lay the groundwork for her later research. While working towards her doctorate, Bishop studied parasitic amoebae and examined potential chemotherapies for the treatment of amoebic diseases including amoebic dysentery.
  
  Her best known work was a comprehensive study of Plasmodium, the malaria parasite, and investigation of various chemotherapies for the disease. Later she studied drug resistance in this parasite, research that proved valuable to the British military in World War II. She discovered the potential for cross-resistance in these parasites during that same period. Bishop also discovered the protozoan Pseudotrichomonas keilini and worked with Aedes aegypti, a malaria vector, as part of her research on the disease. Elected to the Royal Society in 1959, Bishop was the founder of the British Society for Parasitology and served on the World Health Organization's Malaria Committee. (Full article...)
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  A Book of Medical Discourses (1883) by Rebecca Lee Crumpler, M.D.

  
  Rebecca Lee Crumpler (born Rebecca Davis, February 8, 1831 – March 9, 1895) was an American physician, nurse and author. After studying at the New England Female Medical College, in 1864 she became the first African American woman to become a doctor of medicine in the United States. Crumpler was also one of the first female physician authors in the nineteenth century. In 1883, she published A Book of Medical Discourses. The book has two parts that cover the prevention and cure of infantile bowel complaints, and the life and growth of human beings. Dedicated to nurses and mothers, it focuses on maternal and pediatric medical care and was among the first publications written by an African American on the subject of medicine.
  
  Crumpler graduated from medical college at a time when very few African Americans were permitted to attend medical college or publish books. Crumpler first practiced medicine in Boston, primarily serving poor women and children. After the American Civil War ended in 1865, she moved to Richmond, Virginia, believing treating women and children was an ideal way to perform missionary work. Crumpler worked for the Freedmen's Bureau to provide medical care for freedmen and freedwomen. (Full article...)
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  Rapid strep test kit

  
  The rapid strep test (RST) is a rapid antigen detection test (RADT) that is widely used in clinics to assist in the diagnosis of bacterial pharyngitis caused by group A streptococci (GAS), sometimes termed strep throat. There are currently several types of rapid strep test in use, each employing a distinct technology. However, they all work by detecting the presence of GAS in the throat of a person by responding to GAS-specific antigens on a throat swab. (Full article...)
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  A kidney stone, 8 millimeters (0.3 in) in diameter

  
  Kidney stone disease, also known as renal calculus disease, nephrolithiasis or urolithiasis, is a crystallopathy where a solid piece of material (renal calculus) develops in the urinary tract. Renal calculi typically form in the kidney and leave the body in the urine stream. A small calculus may pass without causing symptoms. If a stone grows to more than 5 millimeters (0.2 inches), it can cause blockage of the ureter, resulting in sharp and severe pain in the lower back that often radiates downward to the groin (renal colic). A calculus may also result in blood in the urine, vomiting, or painful urination. About half of people who have had a renal calculus are likely to have another within ten years.
  
  
  Most calculi form by a combination of genetics and environmental factors. Risk factors include high urine calcium levels, obesity, certain foods, some medications, calcium supplements, hyperparathyroidism, gout and not drinking enough fluids. Calculi form in the kidney when minerals in urine are at high concentration. The diagnosis is usually based on symptoms, urine testing, and medical imaging. Blood tests may also be useful. Calculi are typically classified by their location: nephrolithiasis (in the kidney), ureterolithiasis (in the ureter), cystolithiasis (in the bladder), or by what they are made of (calcium oxalate, uric acid, struvite, cystine). (Full article...)
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  An infant with Möbius syndrome and Oromandibular-limb hypogenesis syndrome, exhibiting similar symptoms to Hanhart syndrome

  
  Hanhart syndrome is a broadly classified medical condition consisting of congenital disorders that cause an undeveloped tongue and malformed extremities and fingers. There exist five types of Hanhart syndrome, with the severity and nature of the condition ranging widely on a case-by-case basis. Hanhart syndrome is classified as a rare disease, with approximately 30 known cases having been reported between 1932 and 1991. Early hypotheses believed that the disorder was caused by genetic conditions, with a more recent hypothesis demonstrating that the disorder may be caused by hemorrhagic lesions during prenatal development. The causal mechanism behind this vascular disruption is still unknown. (Full article...)
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  Abida Sophie Jamal (born on 6 June 1966) is a Canadian endocrinologist and former osteoporosis researcher who was at the centre of a scientific misconduct case in the mid-to-late 2010s. Jamal published a high-profile paper suggesting that the heart medication nitroglycerin was a treatment for osteoporosis, and was later demonstrated to have misrepresented her results. She received a lifetime ban from receiving funding from the Canadian Institutes of Health Research and was named directly in their disclosure report, becoming the first person mentioned by name by the institute for scientific misconduct. Jamal was later stripped of her medical license for two years, regaining it in a controversial 3–2 decision. (Full article...)
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  Sir Victor Ewings Negus, MS, FRCS (6 February 1887 – 15 July 1974) was a British surgeon who specialised in laryngology and also made fundamental contributions to comparative anatomy with his work on the structure and evolution of the larynx. He was born and educated in London, studying at King's College School, then King's College London, followed by King's College Hospital. The final years of his medical training were interrupted by the First World War, during which he served with the Royal Army Medical Corps. After the war, he qualified as a surgeon and studied with laryngologists in France and the USA before resuming his career at King's College Hospital where he became a junior surgeon in 1924.
  
  In the 1920s, Negus worked on aspects of both throat surgery and the anatomy of the larynx, the latter work contributing to his degree of Master of Surgery (1924). His surgical innovations included designs for laryngoscopes, bronchoscopes, oesophagoscopes, an operating table, and tracheotomy equipment. His major publications were The Mechanism of the Larynx (1929) and his work on the clinical text Diseases of the Nose and Throat, starting with the fourth edition of 1937. Negus was also awarded several lectureships and published many medical papers and other works on comparative anatomy and laryngology. He became a senior surgeon at King's College Hospital in 1940 and a consulting surgeon in 1946. (Full article...)
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  Allen being given the Medal of Freedom

  
  Beulah Ream Allen (January 26, 1897 – March 17, 1989) was an American nurse, physician, and civilian physician during World War II. After graduating with a nursing degree in 1922, she worked as a supervising nurse and headed the educational department for the LDS Hospital in Salt Lake City. She worked as a hospital inspector for the state of Utah until 1928, when she moved to San Francisco to attend medical school. While earning her degree at the University of California, San Francisco, she worked as a nurse in the Bay Area. Upon her graduation in 1932, she moved to the Philippines, where she opened a medical practice.
  
  During World War II, she volunteered as a civilian surgeon for the United States Army. She was stationed in Baguio and was responsible for the care of nearly 30 soldiers, when the rest of the Army retreated to the Bataan Peninsula. Taken prisoner in 1941, she was held in three internment camps before being liberated. Returning to the United States, she resumed her practice in the Bay Area. She was awarded the Medal of Freedom in 1946. In 1960, she moved her practice to Provo, Utah, where she served as dean of the Brigham Young University College of Nursing until 1964. Allen retired in 1979 and in that year married and relocated to Mesa, Arizona, where she lived until her death in 1989. (Full article...)
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  In Sierra Leone, abortion is a criminal offence. Its abortion law does not specify any grounds for legal abortion. It is unclear whether abortion is permitted to save the life of the mother, as a British judicial decision allowing such abortions is untested in Sierra Leone. Abortion is covered in the country's medical code of ethics, but there is no government training for providers. Prosecution of abortion is uncommon.
  
  Abortion has been illegal since 1861, inheriting a British law. In the 2010s and 2020s, activists, politicians, and international organizations supported proposals to legalise abortion. Religious groups have supported the ban. Sierra Leone ratified the Maputo Protocol in 2015. A bill allowing abortion, first raised in 2010, was approved by Parliament after being introduced by Isata Kabia in 2015. The bill failed as President Ernest Bai Koroma refused to sign it. This law was heavily debated despite a stigma against the subject. In 2022, the government of Julius Maada Bio backed a new reproductive health bill that would lift the abortion ban. (Full article...)
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  The 2009 swine flu pandemic, caused by the H1N1/swine flu/influenza virus and declared by the World Health Organization (WHO) from June 2009 to August 2010, was the third recent flu pandemic involving the H1N1 virus (the first being the 1918–1920 Spanish flu pandemic and the second being the 1977 Russian flu). The first identified human case was in La Gloria, Mexico, a rural town in Veracruz. The virus appeared to be a new strain of H1N1 that resulted from a previous triple reassortment of bird, swine, and human flu viruses which further combined with a Eurasian pig flu virus, leading to the term "swine flu".
  
  Unlike most strains of influenza, the pandemic H1N1/09 virus did not disproportionately infect adults older than 60 years; this was an unusual and characteristic feature of the H1N1 pandemic. Even in the case of previously healthy people, a small percentage develop pneumonia or acute respiratory distress syndrome (ARDS). This manifests itself as increased breathing difficulty and typically occurs three to six days after initial onset of flu symptoms. The pneumonia caused by flu can be either direct viral pneumonia or a secondary bacterial pneumonia. A November 2009 New England Journal of Medicine article recommended that flu patients whose chest X-ray indicates pneumonia receive both antivirals and antibiotics. In particular, it is a warning sign if a child seems to be getting better and then relapses with high fever, as this relapse may be bacterial pneumonia. (Full article...)
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  The pituitary gland on a plate from Gray's Anatomy (1918). The anterior lobe is on the left, and the posterior lobe on the right, both in red.

  
  Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain. If there is decreased secretion of one specific pituitary hormone, the condition is known as selective hypopituitarism. If there is decreased secretion of most or all pituitary hormones, the term panhypopituitarism (pan meaning "all") is used.
  
  The signs and symptoms of hypopituitarism vary, depending on which hormones are undersecreted and on the underlying cause of the abnormality. The diagnosis of hypopituitarism is made by blood tests, but often specific scans and other investigations are needed to find the underlying cause, such as tumors of the pituitary, and the ideal treatment. Most hormones controlled by the secretions of the pituitary can be replaced by tablets or injections. Hypopituitarism is a rare disease, but may be significantly underdiagnosed in people with previous traumatic brain injury. The first description of the condition was made in 1914 by the German physician Dr Morris Simmonds. (Full article...)
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  A person receiving a medication through an intravenous line (cannula)

  
  Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein. The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth. It may also be used to administer medications or other medical therapy such as blood products or electrolytes to correct electrolyte imbalances. Attempts at providing intravenous therapy have been recorded as early as the 1400s, but the practice did not become widespread until the 1900s after the development of techniques for safe, effective use.
  
  The intravenous route is the fastest way to deliver medications and fluid replacement throughout the body as they are introduced directly into the circulatory system and thus quickly distributed. For this reason, the intravenous route of administration is also used for the consumption of some recreational drugs. Many therapies are administered as a "bolus" or one-time dose, but they may also be administered as an extended infusion or drip. The act of administering a therapy intravenously, or placing an intravenous line ("IV line") for later use, is a procedure which should only be performed by a skilled professional. The most basic intravenous access consists of a needle piercing the skin and entering a vein which is connected to a syringe or to external tubing. This is used to administer the desired therapy. In cases where a patient is likely to receive many such interventions in a short period (with consequent risk of trauma to the vein), normal practice is to insert a cannula which leaves one end in the vein, and subsequent therapies can be administered easily through tubing at the other end. In some cases, multiple medications or therapies are administered through the same IV line. (Full article...)
• 

  

  
  Doctor Thomas Hinde (July 10, 1737 – September 28, 1828) was Northern Kentucky's first physician, a member of the British Royal Navy, an American Revolutionary, personal physician to Patrick Henry, and treated General Wolfe when he died in Quebec, Canada. (Full article...)
• 

  

  The bark of willow trees contains salicylic acid, the active metabolite of aspirin, and has been used for millennia to relieve pain and reduce fever.

  
  
  Medicinal plants, also called medicinal herbs, have been discovered and used in traditional medicine practices since prehistoric times. Plants synthesize hundreds of chemical compounds for various functions, including defense and protection against insects, fungi, diseases, and herbivorous mammals.
  
  The earliest historical records of herbs are found from the Sumerian civilization, where hundreds of medicinal plants including opium are listed on clay tablets, c. 3000 BC. The Ebers Papyrus from ancient Egypt, c. 1550 BC, describes over 850 plant medicines. The Greek physician Dioscorides, who worked in the Roman army, documented over 1000 recipes for medicines using over 600 medicinal plants in De materia medica, c. 60 AD; this formed the basis of pharmacopoeias for some 1500 years. Drug research sometimes makes use of ethnobotany to search for pharmacologically active substances, and this approach has yielded hundreds of useful compounds. These include the common drugs aspirin, digoxin, quinine, and opium. The compounds found in plants are diverse, with most in four biochemical classes: alkaloids, glycosides, polyphenols, and terpenes. Few of these are scientifically confirmed as medicines or used in conventional medicine. (Full article...)

Did you know –

• ... that the McMurray test is part of the knee examination in case of suspected tears of the meniscus (pictured)?
• ... that Stauffer syndrome is paraneoplastic liver dysfunction due to renal cell carcinoma?
• ... that periodic fever syndromes or autoinflammatory syndromes include familial Mediterranean fever, hyperimmunoglobulinemia D with recurrent fever, TNF receptor associated periodic syndrome, Muckle–Wells syndrome, familial cold urticaria and periodic fever, aphthous stomatitis, pharyngitis and adenitis, among others?

General images –

The following are images from various Medicine-related articles on Wikipedia.

• 
  Primary care may be provided in community health centers. (from Health care)
• 
  Total healthcare cost per person. Public and private spending. US dollars PPP. For example: $6,319 for Canada in 2022. $12,555 for the US in 2022. (from Health care)
• 
  Guy's Hospital in 1820 (from History of medicine)
• 
  A 12th-century manuscript of the Hippocratic Oath in Greek, one of the most famous aspects of classical medicine that carried into later eras (from History of medicine)
• 
  An American billing clerk preparing a detailed invoice. (1992) (from Medical billing)
• 
  Sketch of Muslim physician Muhammad ibn Zakariya al-Razi (from History of medicine)
• 
  Sometimes traditional medicines include parts of endangered species, such as the slow loris in Southeast Asia. (from Traditional medicine)
• 
  Yarrow, a medicinal plant found in human-occupied caves in the Upper Palaeolithic period. (from History of medicine)
• 
  Hippocrates (c. 460–370 BCE). Known as the "father of medicine". (from History of medicine)
• 
  Most countries have seen a tremendous increase in life expectancy since 1945. However, in southern Africa, the HIV epidemic beginning around 1990 has eroded national health. (from History of medicine)
• 
  Medical personnel place sterilized covers on the arms of the daVinci Xi surgical system, a minimally-invasive robotic surgery system, at the William Beaumont Army Medical Center. (from History of medicine)
• 
  The numbers of Americans lacking health insurance and the uninsured rate from 1987 to 2008 (from Health insurance)
• 
  Botánicas such as this one in Jamaica Plain, Boston, cater to the Latino community and sell folk medicine alongside statues of saints, candles decorated with prayers, lucky bamboo, and other items. (from Traditional medicine)
• 
  Health Expenditure per capita (in PPP-adjusted US$) among several OECD member nations. Data source: OECD's iLibrary (from Health insurance)
• 
  Louis Pasteur experimenting on bacteria, c. 1870 (from History of medicine)
• 
  healthcare expenditure in Japan by age group (from Health insurance)
• 
  National Hospital for Neurology and Neurosurgery in London, United Kingdom is a specialist neurological hospital. (from Health care)
• 
  COVID-19 swab testing in Rwanda (2021). (from History of medicine)
• 
  Life expectancy vs healthcare spending of rich OECD countries. US average of $10,447 in 2018. (from Health care)
• 
  Patient, Surrey County Lunatic Asylum, c. 1850–58. The asylum population in England and Wales rose from 1,027 in 1827 to 74,004 in 1900. (from History of medicine)
• 
  Jackson Memorial Hospital in Miami, the primary teaching hospital of the University of Miami's Miller School of Medicine and the largest hospital in the United States with 1,547 beds (from Health care)
• 
  Zhang Zhongjing – a Chinese pharmacologist, physician, inventor, and writer of the Eastern Han dynasty. (from History of medicine)
• 
  Infographic showing how healthcare data flows within the billing process (from Medical billing)
• 
  A cuneiform terracotta tablet describing a medicinal recipe for poisoning (c. 18th century BCE). Discovered in Nippur, Iraq.
• 
  "Diagram of the causes of mortality in the army in the East" by Florence Nightingale. (from History of medicine)
• 
  Charite in Berlin (from History of medicine)
• 
  American combat surgery during the Pacific War, 1943 (from History of medicine)
• 
  American Civil War hospital at Gettysburg, 1863 (from History of medicine)
• 
  The plinthios brochos as described by Greek physician Heraklas, a sling for binding a fractured jaw. These writings were preserved in one of Oribasius' collections. (from History of medicine)
• 
  Smallpox vaccination in Niger, 1969. A decade later, this was the first infectious disease to be eradicated. (from History of medicine)
• 
  Emil Kraepelin (1856–1926), the founder of modern scientific psychiatry, psychopharmacology and psychiatric genetics. (from History of medicine)
• 
  Seven named physicians and botanists of the Classical world from Vienna Dioscurides. Clockwise from top center: Galen, Dioscorides, Nicander, Rufus of Ephesus, Andreas of Carystus, Apollonius Mus or of Pergamon, Crateuas (from History of medicine)
• 
  Depiction of smallpox in Franciscan Bernardino de Sahagún's history of the conquest of Mexico, Book XII of the Florentine Codex, from the defeated Aztecs' point of view (from History of medicine)
• 
  Curandera performing a limpieza in Cuenca, Ecuador (from Traditional medicine)
• 
  Replica of Antonie van Leeuwenhoek's microscope of the 1670s (from History of medicine)
• 
  Hospital train "Therapist Matvei Mudrov" in Khabarovsk, Russia (from Health care)
• 
  Taoist symbol of Yin and Yang (from Medical ethics)
• 
  Ethical prayer for medical wisdom by Dr Edmond Fernandes (from Medical ethics)
• 
  A Ukrainian monument to the HIV pandemic. (from History of medicine)
• 
  Global concentrations of health care resources, as depicted by the number of physicians per 10,000 individuals, by country. Data is sourced from a World Health Statistics 2010, a WHO report. (from Health care)
• 
  A Neo-Assyrian cuneiform tablet fragment describing medical text (c. 9th to 7th century BCE). (from History of medicine)
• 
  "More Doctors Smoke Camels than Any Other Cigarette" advertisement for Camel cigarettes in the 1940s (from Medical ethics)
• 
  Mexico City epidemic of 1737, with elites calling on the Virgin of Guadalupe (from History of medicine)
• 
  The Quaker-run York Retreat, founded in 1796, gained international prominence as a centre for moral treatment and a model of asylum reform following the publication of Samuel Tuke's Description of the Retreat (1813). (from History of medicine)
• 
  A cochlear implant is a common kind of neural prosthesis, a device replacing part of the human nervous system. (from History of medicine)
• 
  Traditional medicine in a market in Antananarivo, Madagascar (from Traditional medicine)
• 
  A doctor checks a patient's pulse in Meiji-era Japan. (from History of medicine)
• 
  Mandrake (written 'ΜΑΝΔΡΑΓΟΡΑ' in Greek capitals). Naples Dioscurides, 7th century (from History of medicine)
• 
  A 12th-century Byzantine manuscript of the Hippocratic Oath (from Medical ethics)
• 
  Galen (129–216 CE), known for his wide insights into anatomy. (from History of medicine)
• 
  The Edwin Smith Surgical Papyrus, written in the 17th century BCE, contains the earliest recorded reference to the brain. New York Academy of Medicine. (from History of medicine)
• 
  Health expenditure funding types (from Health insurance)
• 
  18th-century medical remedies collected by a British Gentry family (from History of medicine)
• 
  AMA Code of Medical Ethics (from Medical ethics)
• 
  Medicine during the First World War - Medical Transport. (from History of medicine)
• 
  Life Expectancy of the total population at birth among several OECD member nations. Data source: OECD's iLibrary (from Health insurance)
• 
  Statue of Robert Koch, father of medical bacteriology, at Robert-Koch-Platz (Robert Koch square) in Berlin (from History of medicine)
• 
  Health spending by country. Percent of GDP (Gross domestic product). For example: 11.2% for Canada in 2022. 16.6% for the United States in 2022. (from Health care)
• 
  Magical stela or cippus of Horus inscribed with healing encantations (c. 332 to 280 BCE). (from History of medicine)
• 
  The emergency room is often a frontline venue for the delivery of primary medical care. (from Health care)

More Did you know (auto generated)

• ... that Constance Fozzard was told during her surgical training that women with children could not become consultants?
• ... that Tang Zonghai was one of the first advocates for the integration of Chinese and Western medicine?
• ... that fourteenth-century Buddhist monk Tuệ Tĩnh is referred to as a founding father of traditional Vietnamese medicine?
• ... that the Noongar used the Eucalyptus wandoo tree as a medicine and ointment?
• ... that a lack of screening for pregnant women with syphilis in sub-Saharan Africa is associated with increased infant mortality?
• ... that the Anglo-Saxons may have used a mixture of garlic, another Allium, wine, and bovine bile as an eye medicine?

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