Bexlosteride

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Bexlosteride
Bexlosteride.svg
Clinical data
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
Synonyms LY 300502
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
Formula C14H16ClNO
Molar mass 249.73594 g/mol
3D model (Jmol)
 NYesY (what is this?)  (verify)

Bexlosteride is a potent and noncompetitive inhibitor of the enzyme 5α-reductase related to finasteride and dutasteride.[1][2] It is selective for the type I isoform of the enzyme.[1] It advanced to Phase III clinical trials, but development was halted at that stage, and it was never marketed.[3][4]

See also[edit]

References[edit]

  1. ^ a b Chang, Chawnshang (2002). Androgens and androgen receptor : mechanisms, functions, and clinical application. Boston: Kluwer Academic Publishers. ISBN 1-4020-7188-4. 
  2. ^ Lednicer, Daniel (2008). Strategies for Organic Drug Synthesis and Design. New York: Wiley-Interscience. ISBN 0-470-19039-6. 
  3. ^ "Drug Profile: Bexlosteride". Adis Insight. 
  4. ^ Reaxys entry for bexlosteride: Reaxys Registry Number: 6635310