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Triflunordazepam

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(Redirected from Ro5-2904)
Triflunordazepam
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • 5-phenyl-7-(trifluoromethyl)-1,3-dihydro-1,4-benzodiazepin-2-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H11F3N2O
Molar mass304.272 g·mol−1
3D model (JSmol)
  • C1C(=O)NC2=C(C=C(C=C2)C(F)(F)F)C(=N1)C3=CC=CC=C3
  • InChI=1S/C16H11F3N2O/c17-16(18,19)11-6-7-13-12(8-11)15(20-9-14(22)21-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,21,22)
  • Key:UUBMOUNXQFMBQF-UHFFFAOYSA-N
  (verify)

Triflunordazepam (also known as Ro5-2904)[1] is a drug which is a benzodiazepine derivative with high GABAA receptor affinity, and has anticonvulsant effects.[2][3]

See also

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References

[edit]
  1. ^ DE 1136709 
  2. ^ "Ro5-2904". Archives Internationales de Pharmacodynamie et de Thérapie. 154: 131. 1965.
  3. ^ So SS, Karplus M (December 1996). "Genetic neural networks for quantitative structure-activity relationships: improvements and application of benzodiazepine affinity for benzodiazepine/GABAA receptors". Journal of Medicinal Chemistry. 39 (26): 5246–56. doi:10.1021/jm960536o. PMID 8978853.