From Wikipedia, the free encyclopedia
Uldazepam Other names 7-chloro-5-(2-chlorophenyl)-N -prop-2-enoxy-3H -1,4-benzodiazepin-2-amine ATC code
(2Z )-7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-2H -1,4-benzodiazepin-2-one O -allyloxime
CAS Number PubChem CID ChemSpider UNII KEGG CompTox Dashboard (EPA ) Formula C 18 H 15 Cl 2 N 3 O Molar mass 360.24 g/mol g·mol−1 3D model (JSmol )
Clc3ccccc3C/2=N/CC(=N/c1c\2cc(Cl)cc1)\NOC\C=C
InChI=1S/C18H15Cl2N3O/c1-2-9-24-23-17-11-21-18(13-5-3-4-6-15(13)20)14-10-12(19)7-8-16(14)22-17/h2-8,10H,1,9,11H2,(H,22,23)
Y Key:DTMPGSXFUXZBDK-UHFFFAOYSA-N
Y
N Y (what is this?) (verify)
Uldazepam is a drug which is a benzodiazepine derivative.[1] It has sedative and anxiolytic effects similar to those of other benzodiazepines.[2] [3]
Synthesis
Thio thionamide is even more prone to amidine formation than the lactam itself.
Uldazepam synthesis: J. B. Hester, Jr., DE 2005176 (1970); Chem. Abstr., 73: 99,001t (1970).
Rxn of thionamide (2 ) with O -allyl-hydroxylamine gave the oximino (3 ) uldazepam.
See also
References
^ "Uldazepam U 31920" . Psychotropics. Retrieved 12 June 2013 .
^ Oelschläger H, Ellaithy MM, Volke J. Mechanism of the polarographic reduction of the tranquilizer uldazepam. (German). Archiv der Pharmazie (Weinheim) . 1988 Feb;321(2):69-72.
^ Itil TM, Akpinar S, Ozkut H, et al.: Clinical and computerized EEG effects of U-31,920 a new anxiolytic. Current Therapeutic Research . 1974; 16: 642-654.
Alcohols Barbiturates Benzodiazepines Carbamates Flavonoids Imidazoles Kava constituentsMonoureides Neuroactive steroids Nonbenzodiazepines Phenols Piperidinediones Pyrazolopyridines Quinazolinones Volatiles /gases Others/unsorted
3-Hydroxybutanal
α-EMTBL
AA-29504
Alogabat
Avermectins (e.g., ivermectin )
Bromide compounds (e.g., lithium bromide , potassium bromide , sodium bromide )
Carbamazepine
Chloralose
Chlormezanone
Clomethiazole
Darigabat
DEABL
Deuterated etifoxine
Dihydroergolines (e.g., dihydroergocryptine , dihydroergosine , dihydroergotamine , ergoloid (dihydroergotoxine) )
DS2
Efavirenz
Etazepine
Etifoxine
Fenamates (e.g., flufenamic acid , mefenamic acid , niflumic acid , tolfenamic acid )
Fluoxetine
Flupirtine
Hopantenic acid
KRM-II-81
Lanthanum
Lavender oil
Lignans (e.g., 4-O-methylhonokiol , honokiol , magnolol , obovatol )
Loreclezole
Menthyl isovalerate (validolum)
Monastrol
Niacin
Niacinamide
Org 25,435
Phenytoin
Propanidid
Retigabine (ezogabine)
Safranal
Seproxetine
Stiripentol
Sulfonylalkanes (e.g., sulfonmethane (sulfonal) , tetronal , trional )
Terpenoids (e.g., borneol )
Topiramate
Valerian constituents (e.g., isovaleric acid , isovaleramide , valerenic acid , valerenol )