From Wikipedia, the free encyclopedia
Triflubazam
1-methyl-5-phenyl-7-(trifluoromethyl)-1H -1,5-benzodiazepine-2,4(3H ,5H )-dione
CAS Number PubChem CID ChemSpider UNII CompTox Dashboard (EPA ) Formula C 17 H 13 F 3 N 2 O 2 Molar mass −1 3D model (JSmol )
FC(F)(C1=CC(N(C2=CC=CC=C2)C(CC(N3C)=O)=O)=C3C=C1)F
InChI=1S/C17H13F3N2O2/c1-21-13-8-7-11(17(18,19)20)9-14(13)22(16(24)10-15(21)23)12-5-3-2-4-6-12/h2-9H,10H2,1H3
Y Key:DMNPCIKBNDKNTO-UHFFFAOYSA-N
Y (verify)
Triflubazam [1] benzodiazepine derivative, related to clobazam .[2] sedative and anxiolytic effects, with a long half-life and duration of action.[3] [4] [5]
See also References
^ US Patent 3660381 -5-ARYL-1H-1 5-BENZODIAZEPINE-2 4-DIONES
^ Lundbeck Institute (2003). "triflubazam" . psychotropics.dk. Retrieved 17 November 2010 .^ Itil TM, Akpinar S, Fink M: Controlled clinical and quantitative EEG studies of triflubazam (ORF 8063) in patients with anxiety syndrome. Current Therapeutic Research 1976; 19: 307-315
^ Csanalosi I, Pereira-Oran J, Case G, et al.: Triflubazam (ORF 8063), a new benzodiazepine in anxiety neurosis. Current Therapeutic Research 1977; 22: 166-171
^ Nicholson AN, Stone BM, Clarke CH. Effect of the 1,5-benzodiazepines, clobazam and triflubazam, on sleep in man. British Journal of Clinical Pharmacology . 1977 Oct;4(5):567-72.
Alcohols Barbiturates Benzodiazepines Carbamates Flavonoids Imidazoles Kava constituentsMonoureides Neuroactive steroids Nonbenzodiazepines Phenols Piperidinediones Pyrazolopyridines Quinazolinones Volatiles /gases Others/unsorted
3-Hydroxybutanal α-EMTBL AA-29504 Alogabat Avermectins (e.g., ivermectin )Bromide compounds (e.g., lithium bromide , potassium bromide , sodium bromide )Carbamazepine Chloralose Chlormezanone Clomethiazole Darigabat DEABL Deuterated etifoxine Dihydroergolines (e.g., dihydroergocryptine , dihydroergosine , dihydroergotamine , ergoloid (dihydroergotoxine) )DS2 Efavirenz Etazepine Etifoxine Fenamates (e.g., flufenamic acid , mefenamic acid , niflumic acid , tolfenamic acid )Fluoxetine Flupirtine Hopantenic acid KRM-II-81 Lanthanum Lavender oil Lignans (e.g., 4-O-methylhonokiol , honokiol , magnolol , obovatol )Loreclezole Menthyl isovalerate (validolum) Monastrol Niacin Niacinamide Org 25,435 Phenytoin Propanidid Retigabine (ezogabine) Safranal Seproxetine Stiripentol Sulfonylalkanes (e.g., sulfonmethane (sulfonal) , tetronal , trional )Terpenoids (e.g., borneol )Topiramate Valerian constituents (e.g., isovaleric acid , isovaleramide , valerenic acid , valerenol )
