Fletazepam

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Fletazepam
Fletazepam.svg
Systematic (IUPAC) name
7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1,4-benzodiazepine
Clinical data
Legal status
?
Identifiers
CAS number 34482-99-0 YesY
ATC code None
PubChem CID 36834
ChemSpider 33806 YesY
UNII 3AH8OSQ79O YesY
KEGG D04191 YesY
Chemical data
Formula C17H13ClF4N2 
Mol. mass 356.745
 YesY (what is this?)  (verify)

Fletazepam[1] is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, but is mainly notable for its strong muscle relaxant properties.[2]

Fletazepam is most closely related to other N-trifluoroethyl substituted benzodiazepines such as halazepam and quazepam.[3]

See also[edit]

References[edit]

  1. ^ DE 2106175 
  2. ^ Barnett, A.; Goldstein, J.; Fiedler, EP.; Taber, RI. (Nov 1974). "The pharmacology of fletazepam a centrally-acting muscle relaxant.". Arch Int Pharmacodyn Ther 212 (1): 164–74. PMID 4476200. 
  3. ^ Iorio, LC.; Barnett, A.; Billard, W. (Jul 1984). "Selective affinity of 1-N-trifluoroethyl benzodiazepines for cerebellar type 1 receptor sites.". Life Sci 35 (1): 105–13. doi:10.1016/0024-3205(84)90157-7. PMID 6738302.