Thiobutabarbital

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Thiobutabarbital

Systematic (IUPAC) name
5-sec-butyl-5-ethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	2095-57-0
ATC code	None
PubChem	CID 3032373
ChemSpider	2297366^Y
UNII	2N0251U7JH^Y
Synonyms	Thiobutabarbital, Inactin, Brevinarcon, 5-sec-Butyl-5-ethyl-2-thiobarbituric acid
Chemical data
Formula	C₁₀H₁₆N₂O₂S
Mol. mass	228.312 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C10H16N2O2S/c1-4-6(3)10(5-2)7(13)11-9(15)12-8(10)14/h6H,4-5H2,1-3H3,(H2,11,12,13,14,15)^Y Key:IDELNEDBPWKHGK-UHFFFAOYSA-N^Y
Y(what is this?) (verify)

Thiobutabarbital (Inactin, Brevinarcon) is a short-acting barbiturate derivative invented in the 1950s. It has sedative, anticonvulsant and hypnotic effects, and is still used in veterinary medicine for induction in surgical anaesthesia ^[1]

[edit] References

^ Rieg T, Richter K, Osswald H, Vallon V. Kidney function in mice: thiobutabarbital versus alpha-chloralose anesthesia. Naunyn Schmiedebergs Archives of Pharmacology. 2004 Oct;370(4):320-3.

v d e GABA_A receptor PAMs

Barbiturates	Allobarbital Alphenal Amobarbital Aprobarbital Barbexaclone Barbital Benzobarbital Benzylbutylbarbiturate Brallobarbital Brophebarbital Bucolome Butabarbital Butalbital Butobarbital Butallylonal Carbubarb Crotylbarbital Cyclobarbital Cyclopal Difebarbamate Enallylpropymal Ethallobarbital Febarbamate Heptabarb Heptobarbital Hexethal Hexobarbital Metharbital Methohexital Methylphenobarbital Narcobarbital Nealbarbital Pentobarbital Phenobarbital Phetharbital Primidone Prazitone Probarbital Propallylonal Proxibarbal Proxibarbital Reposal Secbutabarbital Secobarbital Sigmodal Spirobarbital Talbutal Tetrabamate Tetrabarbital Thialbarbital Thiamylal Thiobarbital Thiobutabarbital Thiopental Valofane Vinbarbital Vinylbital

Benzodiazepines	Adinazolam Alprazolam Arfendazam Avizafone Bentazepam Bretazenil Bromazepam Brotizolam Camazepam Chlordiazepoxide Ciclotizolam Cinolazepam Clazolam Climazolam Clobazam Clonazepam Clorazepate Clotiazepam Cloxazolam Cyprazepam Delorazepam Diazepam Doxefazepam Elfazepam Estazolam Ethyl carfluzepate Ethyl dirazepate Ethyl loflazepate Etizolam Fletazepam Fludiazepam Flunitrazepam Flurazepam Flutazolam Flutemazepam Flutoprazepam Fosazepam Gidazepam Girisopam Halazepam Haloxazolam Iclazepam Imidazenil Ketazolam Lofendazam Lopirazepam Lopirazepam Loprazolam Lorazepam Lormetazepam Meclonazepam Medazepam Menitrazepam Metaclazepam Mexazolam Midazolam Nerisopam Nimetazepam Nitrazepam Nitrazepate Nordazepam Oxazepam Oxazolam Phenazepam Pinazepam Pivoxazepam Prazepam Premazepam Proflazepam QH-II-66 Quazepam Reclazepam Remimazolam Rilmazafone Ripazepam Ro48-6791 SH-053-R-CH3-2′F Sulazepam Temazepam Tetrazepam Tofisopam Triazolam Triflubazam Uldazepam Zapizolam Zolazepam Zomebazam

Carbamates	Carisbamate Carisoprodol Cyclarbamate Difebarbamate Emylcamate Ethinamate Febarbamate Felbamate Hexapropymate Lorbamate Mebutamate Meprobamate Methocarbamol Nisobamate Pentabamate Phenprobamate Procymate Styramate Tetrabamate Tybamate

Neuroactive steroids	Acebrochol Allopregnanolone Alphadolone Alphaxolone Ganaxolone Hydroxydione Minaxolone Org 20599 THDOC

Nonbenzodiazepines	β-Carbolines: Abecarnil Gedocarnil SL-651,498 ZK-93423; Cyclopyrrolones: Eszopiclone Pagoclone Pazinaclone Suproclone Suriclone Zopiclone; Imidazopyridines: Alpidem Necopidem Saripidem Zolpidem; Pyrazolopyrimidines: Divaplon Fasiplon Indiplon Lorediplon Ocinaplon Panadiplon Taniplon Zaleplon; Others: Adipiplon CGS-8216 CGS-9896 CGS-13767 CGS-20625 CL-218,872 CP-615,003 ELB-139 GBLD-345 L-838,417 NS-2664 NS-2710 NS-11394 Pipequaline ROD-188 RWJ-51204 SB-205,384 SX-3228 TP-003 TPA-023 TP-13 U-89843A U-90042 Y-23684

Phenols	Fospropofol Propofol Thymol

Piperidinediones	Glutethimide Methyprylon Piperidione Pyrithyldione

Pyrazolopyridines	Cartazolate Etazolate ICI-190,622 Tracazolate

Quinazolinones	Afloqualone Cloroqualone Diproqualone Etaqualone Mebroqualone Mecloqualone Methaqualone Methylmethaqualone

Volatiles/gases	2-Methyl-2-butanol Acetone Acetophenone Acetylglycinamide chloral hydrate Benzene Butane Butanol Butylene Centalun Chloral Chloral hydrate Chlorobutanol Chloroform Cyclopropane Desflurane Dichloromethane Diethyl ether Enflurane Ethanol (Alcohol) Ethyl chloride Ethylene Gasoline Halothane Isoflurane Kerosine Menthol Methanol Methoxyflurane Methoxypropane Methylbutanol Nitric oxide Nitrogen Nitrous oxide Paraldehyde Pentanol Propane Propanol Propylene Sevoflurane Toluene Trichloroethanol Trichloroethylene Vinyl ether Xenon

Others	Bromide (Lithium bromide Potassium bromide Sodium bromide) Chloralodol Chloralose Chlormezanone Clomethiazole DEABL Etazepine Ethchlorvynol Etifoxine Etomidate GABA Kavalactones (Kava) Loreclezole Methylpentynol Metomidate Org 25,435 Petrichloral Propanidid Skullcap Stiripentol Sulfonmethane Tetronal Triclofos Trional Valeric acid Valerenic acid (Valerian)