Thiamylal

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Thiamylal
ThiamylalSVG.svg
Systematic (IUPAC) name
5-allyl-5-(1-methylbutyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
Identifiers
CAS number 77-27-0 YesY
ATCvet code QN01AF90
PubChem CID 3032285
DrugBank DB01154
ChemSpider 2297298 YesY
UNII 01T23W89FR YesY
KEGG D06106 YesY
ChEBI CHEBI:9536 YesY
ChEMBL CHEMBL440 YesY
Synonyms Thiamylal, Thioseconal, Surital
Chemical data
Formula C12H18N2O2S 
Mol. mass 254.35 g/mol
 YesY (what is this?)  (verify)

Thiamylal (Surital) is a barbiturate derivative invented in the 1950s. It has sedative, anticonvulsant and hypnotic effects, and is used as a strong but short acting sedative. Thamylal is still in current use, primarily for induction in surgical anaesthesia [1] or as an anticonvulsant to counteract side effects from other anaesthetics. [2] It is the Thiobarbiturate anologue of secobarbital.

References[edit]

  1. ^ Hsieh MY, Hung GY, Hsieh YL, Chang CY, Hwang B. Deep sedation with methohexital or thiamylal with midazolam for invasive procedures in children with acute lymphoblastic leukemia. Acta Paediatrica Taiwan. 2005 Sep-Oct;46(5):294-300.
  2. ^ Tsai CJ, Wang HM, Lu IC, Tai CF, Wang LF, Soo LY, Lu DV. Seizure after local anesthesia for nasopharyngeal angiofibroma. Kaohsiung Journal of Medical Sciences. 2007 Feb;23(2):97-100.