Benzobarbital

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Benzobarbital
Benzobarbital.png
Benzobarbital ball-and-stick.png
Systematic (IUPAC) name
1-benzoyl-5-ethyl-5-phenyl-1,3-diazinane-2,4,6-trione
Clinical data
Legal status
?
Identifiers
CAS number 744-80-9 YesY
ATC code None
PubChem CID 12938
ChemSpider 12402 YesY
UNII YNJ78BD0AH YesY
ChEMBL CHEMBL1338506 N
Synonyms Benzonal
Chemical data
Formula C19H16N2O4 
Mol. mass 336.341 g/mol
 N (what is this?)  (verify)

Benzobarbital (Benzonal) is a barbiturate derivative. It has anticonvulsant effects and has been used for the treatment of epilepsy. [1]

It has similar liver enzyme inducing effects to the closely related drug phenobarbital, which may be exploited in some clinical applications. [2] [3]

References[edit]

  1. ^ Okudzhava, V. M.; Chankvetadze, B. G. (1989). "Pharmacological characteristics of an anti-convulsive drug Benzonal and the evaluation of its therapeutic effectiveness (literature review)". Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (in Russian) (Moscow) 89 (11): 136–145. ISSN 0044-4588. PMID 2696306.  edit
  2. ^ Nadzhimutdinov, K. N.; Khakimov, Z. Z.; Kabulov, Sh. M. (1992). "The advantages of benzonal as an inducer of the liver mono-oxygenase enzyme system compared to phenobarbital". Eksperimental'naia i klinicheskaia farmakologiia (in Russian) (Moscow) 55 (1): 68–71. ISSN 0869-2092. PMID 1305441.  edit
  3. ^ Novozheeva, T. P.; Saratikov, A. S.; Grishanova, A. U.; Gutkina, N. I.; Akhmedzhanov, R. R.; Khatsenko, O. G.; Kozlovskaia, N. E. (1991). "Benzonal--a phenobarbital-type of inducer of the mono-oxygenase system". Biulleten' eksperimental'noi biologii i meditsiny (in Russian) (Moscow) 111 (2): 163–165. ISSN 0365-9615. OCLC 613807502. PMID 1854958.  edit