|This article does not cite any references or sources. (December 2013)|
In the United States, MS Contin is available in tablet and liquid formulas in doses of 15mg, 20mg, 30mg, 60mg, 100mg and 200mg. In Australia, MS Contin tablets are available in doses of 5mg, 10mg, 15mg, 30mg, 60mg, 100mg and 200mg, and as a suspension, in doses of 20mg, 30mg, 60mg, 100mg and 200mg. It is typically prescribed in cases of severe pain where prolonged opioid therapy is indicated.
MS Contin is a DEA Schedule II substance in the United States, and is a Schedule 8 (controlled) drug in Australia.
Alternative sustained release morphine sulfate formulations made and marketed by other pharmaceutical companies include King Pharmaceuticals' Avinza and Actavis Pharmaceuticals' Kadian. Kadian is available in various strengths. There has been some concern[by whom?] regarding the issue that some capsules contain pellets (made by the process of extrusion and Spheronization while others contain powder. Pellet (spheroid) formulations (made by extrusion and spheronization) can be used for controlled release of the drug in the body whereas powder filled pellets generally cannot.