Cyclorphan

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Cyclorphan
Cyclorphan structure.svg
Systematic (IUPAC) name
3-hydroxy-N-cyclopropylmethylmorphinan
Clinical data
Legal status ?
Identifiers
CAS number 4163-15-9
ATC code ?
PubChem CID 5359966
ChemSpider 4514407
ChEMBL CHEMBL49269
Chemical data
Formula C20H27NO 
Mol. mass 297.434 g/mol

Cyclorphan is a hallucinogenic opioid mixed agonist–antagonist related to levorphanol discovered in the late 1960s. It is not marketed as an analgesic because of side effects related to its impact on the kappa opioid receptor,[1][2] but has found some use as a research chemical on and off since its discovery.

References[edit]

  1. ^ Herling, S, Hein, DW, Nemeth, MA, Valentino, RJ, Woods, JH. (Jan 1982). "Discriminative stimulus, antagonist, and rate-decreasing effects of cyclorphan: multiple modes of action". Life Sciences 30 (4): 331–41. doi:10.1016/0024-3205(82)90569-0. PMID 6122153. 
  2. ^ Bertalmio, AJ, Woods, JH. (1992). "Discriminative stimulus effects of cyclorphan: selective antagonism with naltrexone". Psychopharmacology (Berlin) 106 (2): 189–94. PMID 1347952.