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Sigmodal Legal status
5-(2-bromoprop-2-en-1-yl)-5-(1-methylbutyl)pyrimidine-2,4,6(1H ,3H ,5H )-trione
CAS Number PubChem CID ChemSpider UNII CompTox Dashboard (EPA ) ECHA InfoCard 100.013.575 Formula C 12 H 17 Br N 2 O 3 Molar mass 317.183 g·mol−1 3D model (JSmol )
CCCC(C)C1(C(=O)NC(=O)NC1=O)CC(=C)Br
InChI=1S/C12H17BrN2O3/c1-4-5-7(2)12(6-8(3)13)9(16)14-11(18)15-10(12)17/h7H,3-6H2,1-2H3,(H2,14,15,16,17,18)
N Key:ZGVCLZRQOUEZHG-UHFFFAOYSA-N
N
N Y (what is this?) (verify)
Sigmodal (Rectidon) is a barbiturate derivative. It has sedative , hypnotic and anticonvulsant properties, and was used in surgical anaesthesia in the 1950s, and frequently appeared in drug mixtures in the 60's.
[1]
[2]
It was never widely used compared to better known barbiturates such as thiopental , and has now been replaced by newer drugs with a better safety profile.
References
^ Meder F (1952). "[Our experiences with rectidon basal anesthesia]". Zentralblatt Fur Gynakologie (in German). 74 (48): 1895–6. PMID 13050081 .
^ Frommolt G (November 1952). "[On rectidon basis narcosis]". Die Medizinische (in German). 20 (47): 1503–4. PMID 13024592 .
Alcohols Barbiturates Benzodiazepines Carbamates Flavonoids Imidazoles Kava constituentsMonoureides Neuroactive steroids Nonbenzodiazepines Phenols Piperidinediones Pyrazolopyridines Quinazolinones Volatiles /gases Others/unsorted
3-Hydroxybutanal
α-EMTBL
AA-29504
Alogabat
Avermectins (e.g., ivermectin )
Bromide compounds (e.g., lithium bromide , potassium bromide , sodium bromide )
Carbamazepine
Chloralose
Chlormezanone
Clomethiazole
Darigabat
DEABL
Deuterated etifoxine
Dihydroergolines (e.g., dihydroergocryptine , dihydroergosine , dihydroergotamine , ergoloid (dihydroergotoxine) )
DS2
Efavirenz
Etazepine
Etifoxine
Fenamates (e.g., flufenamic acid , mefenamic acid , niflumic acid , tolfenamic acid )
Fluoxetine
Flupirtine
Hopantenic acid
KRM-II-81
Lanthanum
Lavender oil
Lignans (e.g., 4-O-methylhonokiol , honokiol , magnolol , obovatol )
Loreclezole
Menthyl isovalerate (validolum)
Monastrol
Niacin
Niacinamide
Org 25,435
Phenytoin
Propanidid
Retigabine (ezogabine)
Safranal
Seproxetine
Stiripentol
Sulfonylalkanes (e.g., sulfonmethane (sulfonal) , tetronal , trional )
Terpenoids (e.g., borneol )
Topiramate
Valerian constituents (e.g., isovaleric acid , isovaleramide , valerenic acid , valerenol )